Investigating the role of the fat mass and obesity associated gene (Fto) in obesity

<p>In 2007, a genome wide association study identified a SNP in intron 1 of FTO with increased BMI. Homozygous risk allele carriers are on average three kg heavier than those homozygous for the protective allele. Mouse models have been made, including a conditional knockout, which is lean when...

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Dettagli Bibliografici
Autore principale: McMurray, F
Altri autori: Cox, R
Natura: Tesi
Lingua:English
Pubblicazione: 2013
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