Alternate splicing of the p53 inhibitor HDMX offers a superior prognostic biomarker than p53 mutation in human cancer.

Alternate splicing of the p53 inhibitor HDMX offers a superior prognostic biomarker than p53 mutation in human cancer.

Conventional high-grade osteosarcoma is the most common primary bone malignancy. Although altered expression of the p53 inhibitor HDMX (Mdmx/Mdm4) is associated with cancer risk, progression, and outcome in other tumor types, little is known about its role in osteosarcoma. High expression of the Hdm...

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Detalhes bibliográficos
Main Authors: Lenos, K, Grawenda, A, Lodder, K, Kuijjer, M, Teunisse, A, Repapi, E, Grochola, L, Bartel, F, Hogendoorn, P, Wuerl, P, Taubert, H, Cleton-Jansen, A, Bond, G, Jochemsen, A
Formato: Journal article
Idioma:English
Publicado em: 2012

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