Pharmacological inhibition of CCR9 is a novel approach in the treatment of inflammatory bowel disease

Pharmacological inhibition of CCR9 is a novel approach in the treatment of inflammatory bowel disease

Bibliografiske detaljer
Main Authors:	Bekker, P, Keshav, S, Wei, Z, Ertl, L, Wang, Y, Lai, N, Wright, J, Ungashe, S, Schall, T
Format:	Journal article
Udgivet:	2007

Lignende værker

Characterization of CCX282-B, an orally bioavailable antagonist of the CCR9 chemokine receptor, for treatment of inflammatory bowel disease.
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Udgivet: (2010)

Ccx282-B, an orally active inhibitor of chemokine receptor Ccr9, shows anti-inflammatory and clinical activity in the treatment of Crohn's disease
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Udgivet: (2007)

Traficet-EN (CCX282-B), an orally active inhibitor of chemokine receptor CCR9, for treatment of Crohn's disease
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Udgivet: (2007)

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MEDI 167-Discovery of the highly potent, selective and orally bioavailable CCR9 antagonist CCX282-B
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Traficet-EN, an Oral CCR9-Specific Antagonist, induces high levels of remission in the open-label Phase of PROTECT-1 in Crohn's Disease
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Traficet-EN, an oral CCR9-specific antagonist, induces high levels of remission in the open-label phase of PROTECT-1 in Crohn's disease
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PROTECT-1 Maintenance Phase Study Results demonstrate efficacy of the Intestine-Specific Chemokine Receptor Antagonist CCX282-B (Traficet-EN) in Crohn's Disease
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PROTECT-1 Study Demonstrated Efficacy of the Intestine-Specific Chemokine Receptor Antagonist CCX282-B (Traficet-EN) in Treatment of Patients with Moderate to Severe Crohn's Disease
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Pharmacological Inhibition of CCR2 Signaling Exacerbates Exercise-Induced Inflammation Independently of Neutrophil Infiltration and Oxidative Stress
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NLRP3 inflammasome inhibition of OP9 cells enhance therapy for inflammatory bowel disease
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PROTECT-1: A prospective randomized trial of CCX282-B (Traficet-EN), a novel oral therapy targeting chemokine receptor 9 in Crohn's disease
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