CCR6, a CC chemokine receptor that interacts with macrophage inflammatory protein 3alpha and is highly expressed in human dendritic cells.

CCR6, a CC chemokine receptor that interacts with macrophage inflammatory protein 3alpha and is highly expressed in human dendritic cells.

Dendritic cells initiate immune responses by ferrying antigen from the tissues to the lymphoid organs for presentation to lymphocytes. Little is known about the molecular mechanisms underlying this migratory behavior. We have identified a chemokine receptor which appears to be selectively expressed...

ver descrição completa

Detalhes bibliográficos
Main Authors:	Greaves, D, Wang, W, Dairaghi, D, Dieu, M, Saint-Vis, B, Franz-Bacon, K, Rossi, D, Caux, C, McClanahan, T, Gordon, S, Zlotnik, A, Schall, T
Formato:	Journal article
Idioma:	English
Publicado em:	1997

Registos relacionados

Abduction of chemokine elements by herpesviruses
Por: Dairaghi, D, et al.
Publicado em: (1998)

Cc chemokine receptor 9 (ccr9) antagonist ameliorates experimental ileitis and colitis
Por: Wei, Z, et al.
Publicado em: (2005)

Expression of a membrane associated CC-chemokine inhibitor protein reduces in vitro macrophage chemotaxis to CC chemokines
Por: McNeill, E, et al.
Publicado em: (2010)

A new class of membrane-bound chemokine with a CX3C motif.
Por: Bazan, J, et al.
Publicado em: (1997)

Membrane-bound CC chemokine inhibitor 35K provides localized inhibition of CC chemokine activity in vitro and in vivo.
Por: Bursill, C, et al.
Publicado em: (2006)

Atherosclerosis: role of chemokines and macrophages.
Por: Lucas, A, et al.
Publicado em: (2001)

Chemokines and myeloid cell recruitment.
Por: Greaves, D, et al.
Publicado em: (2000)

Characterization of CCX282-B, an orally bioavailable antagonist of the CCR9 chemokine receptor, for treatment of inflammatory bowel disease.
Por: Walters, M, et al.
Publicado em: (2010)

Adenoviral delivery of CC-chemokine inhibitor '35K' reduces macrophage recruitment and atherosclerosis in ApoE knockout mice
Por: Bursill, C, et al.
Publicado em: (2004)

A membrane-bound vaccinia viral protein 'mem35k' blocks CC-chemokine induced cell migration and CC-chemokine activity in vitro
Por: Bursill, C, et al.
Publicado em: (2005)

Adenoviral delivery of a Cc-chemokine inhibitor, "35k," reduces macrophage recruitment and atherosclerosis in Apoe knockout mice
Por: Bursill, C, et al.
Publicado em: (2004)

CC chemokine receptors and chronic inflammation--therapeutic opportunities and pharmacological challenges.
Por: White, G, et al.
Publicado em: (2013)

Adenoviral-mediated delivery of a viral chemokine binding protein blocks CC-chemokine activity in vitro and in vivo.
Por: Bursill, C, et al.
Publicado em: (2003)

Contrasting in vitro vs. in vivo effects of a cell membrane-specific CC-chemokine binding protein on macrophage chemotaxis.
Por: McNeill, E, et al.
Publicado em: (2014)

Site-directed mutagenesis of the CC chemokine binding protein 35K-Fc reveals residues essential for activity and mutations that increase the potency of CC chemokine blockade.
Por: White, G, et al.
Publicado em: (2011)

Analysis of the CC chemokine receptor 5 (CCR5)Delta 32 polymorphism in Behcet's disease (vol 31, pg 11, 2004)
Por: Yang, X, et al.
Publicado em: (2005)

Broad-spectrum CC-chemokine blockade by gene transfer inhibits macrophage recruitment and atherosclerotic plaque formation in apolipoprotein E-knockout mice.
Por: Bursill, C, et al.
Publicado em: (2004)

Interleukin-4 induction of the CC chemokine TARC (CCL17) in murine macrophages is mediated by multiple STAT6 sites in the TARC gene promoter.
Por: Liddiard, K, et al.
Publicado em: (2006)

Interleukin-4 induction of the CC chemokine TARC (CCL17) in murine macrophages is mediated by multiple STAT6 sites in the TARC gene promoter
Por: Liddiard, K, et al.
Publicado em: (2006)

Interleukin-4 induction of the CC chemokine TARC (CCL17) in murine macrophages is mediated by multiple STAT6 sites in the TARC gene promoter
Por: Liddiard, K, et al.
Publicado em: (2006)

Ccx282-B, an orally active inhibitor of chemokine receptor Ccr9, shows anti-inflammatory and clinical activity in the treatment of Crohn's disease
Por: Keshav, S, et al.
Publicado em: (2007)

Adenoviral mediated delivery of a vaccinia viral protein (35K) blocks CC-chemokine activity in vitro and in vivo and may therefore be a useful therapeutic strategy to reduce the initiation and progression of CC-chemokine induced atherosclerosis
Por: Bursill, C, et al.
Publicado em: (2003)

Expression and function of the chemokine receptor CCR7 in thyroid carcinomas.
Por: Sancho, M, et al.
Publicado em: (2006)

Traficet-EN (CCX282-B), an orally active inhibitor of chemokine receptor CCR9, for treatment of Crohn's disease
Por: Bekker, P, et al.
Publicado em: (2007)

Lentiviral gene transfer to reduce atherosclerosis progression by long-term CC-chemokine inhibition.
Por: Bursill, C, et al.
Publicado em: (2009)

Hepatic CC chemokines control the magnitude of the inflammatory response within the injured rodent brain
Por: Campbell, S, et al.
Publicado em: (2004)

Control of dendritic cell trafficking in lymphatics by chemokines
Por: Johnson, L, et al.
Publicado em: (2014)

Control of dendritic cell trafficking in lymphatics by chemokines.
Por: Johnson, L, et al.
Publicado em: (2014)

Chemokines, chemokine receptors and atherosclerosis
Por: John, A, et al.
Publicado em: (2005)

Gene transfer of a broad spectrum CC-chemokine inhibitor reduces macrophage recruitment and smooth muscle content in vein graft atherosclerosis in apolipoprotein E-knockout mice
Por: Ali, Z, et al.
Publicado em: (2005)

Differential production of inflammatory chemokines by murine dendritic cell subsets.
Por: Proietto, A, et al.
Publicado em: (2004)

Generation and site-directed mutagenesis of a 35K-Fc fusion protein with increased potency of CC chemokine blockade
Por: White, G, et al.
Publicado em: (2010)

The duffy antigen/receptor for chemokines exists in an oligomeric form in living cells and functionally antagonizes CCR5 signaling through hetero-oligomerization.
Por: Chakera, A, et al.
Publicado em: (2008)

Hydrodynamic gene delivery of CC chemokine binding Fc fusion proteins to target acute vascular inflammation in vivo.
Por: McNeill, E, et al.
Publicado em: (2015)

Linked chromosome 16q13 chemokines, macrophage-derived chemokine, fractalkine, and thymus- and activation-regulated chemokine, are expressed in human atherosclerotic lesions.
Por: Greaves, D, et al.
Publicado em: (2001)

Adenoviral-mediated delivery of a CC-chemokine inhibitor ('35K') attenuates atherosclerotic plaque formation in apolipoprotein E-knockout mice
Por: Bursill, C, et al.
Publicado em: (2004)

The herpesvirus 8-encoded chemokine vMIP-II, but not the poxvirus-encoded chemokine MC148, inhibits the CCR10 receptor.
Por: Lüttichau, H, et al.
Publicado em: (2001)

Variants of the chemokine receptor CCR5 are associated with severe bronchiolitis caused by respiratory syncytial virus.
Por: Hull, J, et al.
Publicado em: (2003)

Adenoviral mediated delivery of a CC chemokine (CK) inhibitor ("35K") attenuates atherosclerotic plaque formation in apolipoprotein E-knockout mice
Por: Bursill, C, et al.
Publicado em: (2004)

Gene transfer of a broad spectrum CC-chemokine inhibitor reduces vein graft atherosclerosis in apolipoprotein E-knockout mice.
Por: Ali, Z, et al.
Publicado em: (2005)