CCR6, a CC chemokine receptor that interacts with macrophage inflammatory protein 3alpha and is highly expressed in human dendritic cells.

CCR6, a CC chemokine receptor that interacts with macrophage inflammatory protein 3alpha and is highly expressed in human dendritic cells.

Dendritic cells initiate immune responses by ferrying antigen from the tissues to the lymphoid organs for presentation to lymphocytes. Little is known about the molecular mechanisms underlying this migratory behavior. We have identified a chemokine receptor which appears to be selectively expressed...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Greaves, D, Wang, W, Dairaghi, D, Dieu, M, Saint-Vis, B, Franz-Bacon, K, Rossi, D, Caux, C, McClanahan, T, Gordon, S, Zlotnik, A, Schall, T
Format:	Journal article
Sprache:	English
Veröffentlicht:	1997

Ähnliche Einträge

Abduction of chemokine elements by herpesviruses
von: Dairaghi, D, et al.
Veröffentlicht: (1998)

Cc chemokine receptor 9 (ccr9) antagonist ameliorates experimental ileitis and colitis
von: Wei, Z, et al.
Veröffentlicht: (2005)

Expression of a membrane associated CC-chemokine inhibitor protein reduces in vitro macrophage chemotaxis to CC chemokines
von: McNeill, E, et al.
Veröffentlicht: (2010)

A new class of membrane-bound chemokine with a CX3C motif.
von: Bazan, J, et al.
Veröffentlicht: (1997)

Membrane-bound CC chemokine inhibitor 35K provides localized inhibition of CC chemokine activity in vitro and in vivo.
von: Bursill, C, et al.
Veröffentlicht: (2006)

Atherosclerosis: role of chemokines and macrophages.
von: Lucas, A, et al.
Veröffentlicht: (2001)

Chemokines and myeloid cell recruitment.
von: Greaves, D, et al.
Veröffentlicht: (2000)

Characterization of CCX282-B, an orally bioavailable antagonist of the CCR9 chemokine receptor, for treatment of inflammatory bowel disease.
von: Walters, M, et al.
Veröffentlicht: (2010)

Adenoviral delivery of CC-chemokine inhibitor '35K' reduces macrophage recruitment and atherosclerosis in ApoE knockout mice
von: Bursill, C, et al.
Veröffentlicht: (2004)

A membrane-bound vaccinia viral protein 'mem35k' blocks CC-chemokine induced cell migration and CC-chemokine activity in vitro
von: Bursill, C, et al.
Veröffentlicht: (2005)

Adenoviral delivery of a Cc-chemokine inhibitor, "35k," reduces macrophage recruitment and atherosclerosis in Apoe knockout mice
von: Bursill, C, et al.
Veröffentlicht: (2004)

CC chemokine receptors and chronic inflammation--therapeutic opportunities and pharmacological challenges.
von: White, G, et al.
Veröffentlicht: (2013)

Adenoviral-mediated delivery of a viral chemokine binding protein blocks CC-chemokine activity in vitro and in vivo.
von: Bursill, C, et al.
Veröffentlicht: (2003)

Contrasting in vitro vs. in vivo effects of a cell membrane-specific CC-chemokine binding protein on macrophage chemotaxis.
von: McNeill, E, et al.
Veröffentlicht: (2014)

Site-directed mutagenesis of the CC chemokine binding protein 35K-Fc reveals residues essential for activity and mutations that increase the potency of CC chemokine blockade.
von: White, G, et al.
Veröffentlicht: (2011)

Analysis of the CC chemokine receptor 5 (CCR5)Delta 32 polymorphism in Behcet's disease (vol 31, pg 11, 2004)
von: Yang, X, et al.
Veröffentlicht: (2005)

Broad-spectrum CC-chemokine blockade by gene transfer inhibits macrophage recruitment and atherosclerotic plaque formation in apolipoprotein E-knockout mice.
von: Bursill, C, et al.
Veröffentlicht: (2004)

Interleukin-4 induction of the CC chemokine TARC (CCL17) in murine macrophages is mediated by multiple STAT6 sites in the TARC gene promoter.
von: Liddiard, K, et al.
Veröffentlicht: (2006)

Interleukin-4 induction of the CC chemokine TARC (CCL17) in murine macrophages is mediated by multiple STAT6 sites in the TARC gene promoter
von: Liddiard, K, et al.
Veröffentlicht: (2006)

Interleukin-4 induction of the CC chemokine TARC (CCL17) in murine macrophages is mediated by multiple STAT6 sites in the TARC gene promoter
von: Liddiard, K, et al.
Veröffentlicht: (2006)

Ccx282-B, an orally active inhibitor of chemokine receptor Ccr9, shows anti-inflammatory and clinical activity in the treatment of Crohn's disease
von: Keshav, S, et al.
Veröffentlicht: (2007)

Adenoviral mediated delivery of a vaccinia viral protein (35K) blocks CC-chemokine activity in vitro and in vivo and may therefore be a useful therapeutic strategy to reduce the initiation and progression of CC-chemokine induced atherosclerosis
von: Bursill, C, et al.
Veröffentlicht: (2003)

Expression and function of the chemokine receptor CCR7 in thyroid carcinomas.
von: Sancho, M, et al.
Veröffentlicht: (2006)

Traficet-EN (CCX282-B), an orally active inhibitor of chemokine receptor CCR9, for treatment of Crohn's disease
von: Bekker, P, et al.
Veröffentlicht: (2007)

Lentiviral gene transfer to reduce atherosclerosis progression by long-term CC-chemokine inhibition.
von: Bursill, C, et al.
Veröffentlicht: (2009)

Hepatic CC chemokines control the magnitude of the inflammatory response within the injured rodent brain
von: Campbell, S, et al.
Veröffentlicht: (2004)

Control of dendritic cell trafficking in lymphatics by chemokines
von: Johnson, L, et al.
Veröffentlicht: (2014)

Control of dendritic cell trafficking in lymphatics by chemokines.
von: Johnson, L, et al.
Veröffentlicht: (2014)

Chemokines, chemokine receptors and atherosclerosis
von: John, A, et al.
Veröffentlicht: (2005)

Gene transfer of a broad spectrum CC-chemokine inhibitor reduces macrophage recruitment and smooth muscle content in vein graft atherosclerosis in apolipoprotein E-knockout mice
von: Ali, Z, et al.
Veröffentlicht: (2005)

Differential production of inflammatory chemokines by murine dendritic cell subsets.
von: Proietto, A, et al.
Veröffentlicht: (2004)

Generation and site-directed mutagenesis of a 35K-Fc fusion protein with increased potency of CC chemokine blockade
von: White, G, et al.
Veröffentlicht: (2010)

Linked chromosome 16q13 chemokines, macrophage-derived chemokine, fractalkine, and thymus- and activation-regulated chemokine, are expressed in human atherosclerotic lesions.
von: Greaves, D, et al.
Veröffentlicht: (2001)

The duffy antigen/receptor for chemokines exists in an oligomeric form in living cells and functionally antagonizes CCR5 signaling through hetero-oligomerization.
von: Chakera, A, et al.
Veröffentlicht: (2008)

Hydrodynamic gene delivery of CC chemokine binding Fc fusion proteins to target acute vascular inflammation in vivo.
von: McNeill, E, et al.
Veröffentlicht: (2015)

Adenoviral-mediated delivery of a CC-chemokine inhibitor ('35K') attenuates atherosclerotic plaque formation in apolipoprotein E-knockout mice
von: Bursill, C, et al.
Veröffentlicht: (2004)

Variants of the chemokine receptor CCR5 are associated with severe bronchiolitis caused by respiratory syncytial virus.
von: Hull, J, et al.
Veröffentlicht: (2003)

The herpesvirus 8-encoded chemokine vMIP-II, but not the poxvirus-encoded chemokine MC148, inhibits the CCR10 receptor.
von: Lüttichau, H, et al.
Veröffentlicht: (2001)

Adenoviral mediated delivery of a CC chemokine (CK) inhibitor ("35K") attenuates atherosclerotic plaque formation in apolipoprotein E-knockout mice
von: Bursill, C, et al.
Veröffentlicht: (2004)

Gene transfer of a broad spectrum CC-chemokine inhibitor reduces vein graft atherosclerosis in apolipoprotein E-knockout mice.
von: Ali, Z, et al.
Veröffentlicht: (2005)