Neoadjuvant immune checkpoint blockade in women with mismatch repair deficient endometrial cancer: a phase I study

Neoadjuvant immune checkpoint blockade in women with mismatch repair deficient endometrial cancer: a phase I study

Neoadjuvant immune checkpoint blockade (ICB) has shown unprecedented activity in mismatch repair deficient (MMRd) colorectal cancers, but its effectiveness in MMRd endometrial cancer (EC) remains unknown. In this investigator-driven, phase I, feasibility study (NCT04262089), 10 women with MMRd EC of...

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Bibliographic Details
Main Authors:	Eerkens, AL, Brummel, K, Vledder, A, Paijens, ST, Requesens, M, Loiero, D, van Rooij, N, Plat, A, Haan, F, Klok, P, Yigit, R, Roelofsen, T, de Lange, NM, Klomp, R, Church, D, ter Elst, A, Wardenaar, R, Spierings, D, Foijer, F, Koelzer, VH, Bosse, T, Bart, J, Jalving, M, Reyners, AKL
Format:	Journal article
Language:	English
Published:	Nature Research 2024

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