In vivo generated CD25(+)CD4(+) T cells regulate islet allograft rejection by preventing effector cell migration into the graft

Geahča maid

• Visualization of the in vivo generation of donor antigen-specific effector CD8+ T cells during mouse cardiac allograft rejection: in vivo effector CD8+ T cell generation during allograft rejection.
  Dahkki: Gilot, B, et al.
  Almmustuhtton: (2000)
• GITR ligation blocks allograft protection by induced CD25+CD4+ regulatory T cells without enhancing effector T-cell function.
  Dahkki: Bushell, A, et al.
  Almmustuhtton: (2007)
• Pretransplant blood transfusion with additional immunotherapy tolerizes recipients to islet allografts
  Dahkki: Bortecen, K, et al.
  Almmustuhtton: (2005)
• The generation of CD25+ CD4+ regulatory T cells that prevent allograft rejection does not compromise immunity to a viral pathogen.
  Dahkki: Bushell, A, et al.
  Almmustuhtton: (2005)
• CD25+CD4+ regulatory T cells develop in mice not only during spontaneous acceptance of liver allografts but also after acute allograft rejection.
  Dahkki: Steger, U, et al.
  Almmustuhtton: (2006)