In vivo generated CD25(+)CD4(+) T cells regulate islet allograft rejection by preventing effector cell migration into the graft

In vivo generated CD25(+)CD4(+) T cells regulate islet allograft rejection by preventing effector cell migration into the graft

Xehetasun bibliografikoak
Egile Nagusiak:	Bortecen, K, Bushell, A, Martin, L, Wood, K
Formatua:	Conference item
Argitaratua:	2005

Antzeko izenburuak

Visualization of the in vivo generation of donor antigen-specific effector CD8+ T cells during mouse cardiac allograft rejection: in vivo effector CD8+ T cell generation during allograft rejection.
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GITR ligation blocks allograft protection by induced CD25+CD4+ regulatory T cells without enhancing effector T-cell function.
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Pretransplant blood transfusion with additional immunotherapy tolerizes recipients to islet allografts
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The generation of CD25+ CD4+ regulatory T cells that prevent allograft rejection does not compromise immunity to a viral pathogen.
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CD25+CD4+ regulatory T cells develop in mice not only during spontaneous acceptance of liver allografts but also after acute allograft rejection.
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Interferon-gamma conditioning ex vivo generates CD25+CD62L+Foxp3+ regulatory T cells that prevent allograft rejection: potential avenues for cellular therapy.
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CD25+CD4+ regulatory T cells generated by exposure to a model protein antigen prevent allograft rejection: antigen-specific reactivation in vivo is critical for bystander regulation.
nork: Karim, M, et al.
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CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses.
nork: Kingsley, C, et al.
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Anti-OX40 prevents effector T-cell accumulation and CD8+ T-cell mediated skin allograft rejection.
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Regulation of transplant arteriosclerosis by CD25+CD4+ T cells generated to alloantigen in vivo.
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Direct functional activation of CD4+CD25+Foxp3+T cells by intravenous immunoglobulins promotes skin allograft acceptance.
nork: Tha-In, T, et al.
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Alloantigen-induced CD25+CD4+ regulatory T cells can develop in vivo from CD25-CD4+ precursors in a thymus-independent process.
nork: Karim, M, et al.
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CD40-CD40 ligand-independent activation of CD8+ T cells can trigger allograft rejection.
nork: Jones, N, et al.
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CD40-CD40L independent activation of CD8+T cells can trigger allograft rejection.
nork: Jones, N, et al.
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Effector and Regulatory T Cell Trafficking in Corneal Allograft Rejection
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mCMV Infection Increases Migration of Graft-Reactive CD8(+) T Cells into the Allograft Impairing Regulatory T Cell Survival
nork: Ferrer, I, et al.
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Innate immune signals required for islet and cardiac allograft rejection are regulated by CD45.
nork: Camirand, G, et al.
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Cutting edge: CD4+CD25+ alloantigen-specific immunoregulatory cells that can prevent CD8+ T cell-mediated graft rejection: implications for anti-CD154 immunotherapy.
nork: van Maurik, A, et al.
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Differential susceptibility of heart, skin, and islet allografts to T cell-mediated rejection.
nork: Jones, N, et al.
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Coinhibitory T-Cell Signaling in Islet Allograft Rejection and Tolerance
nork: Wayne Truong, et al.
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Islet allograft rejection can be mediated by CD4+, alloantigen experienced, direct pathway T cells of TH1 and TH2 cytokine phenotype.
nork: Barbara, J, et al.
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Cultured keratinocyte grafts are recognized, but not rejected by CD8+ T cells in vivo.
nork: Tinois, E, et al.
Argitaratua: (1989)

Differences in the Contribution of CD4+ T Cells to Proislet and Islet Allograft Rejection Correlate with Constitutive Class II MHC Alloantigen Expression
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Mesenchymal stem cells prevent the rejection of fully allogenic islet grafts by the immunosuppressive activity of matrix metalloproteinase-2 and -9.
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CD4hiCD8low Double-Positive T Cells Are Associated with Graft Rejection in a Nonhuman Primate Model of Islet Transplantation
nork: Yun Jung Choi, et al.
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Effect of graft perfusion with two CD45 monoclonal antibodies on incidence of kidney allograft rejection.
nork: Brewer, Y, et al.
Argitaratua: (1989)

Kidney allograft rejection is associated with an imbalance of B cells, regulatory T cells and differentiated CD28-CD8+ T cells: analysis of a cohort of 1095 graft biopsies
nork: Hoa Le Mai, et al.
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Autoreactive effector/memory CD4+ and CD8+ T cells infiltrating grafted and endogenous islets in diabetic NOD mice exhibit similar T cell receptor usage.
nork: Ramiro Diz, et al.
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Inhibition of Allograft Inflammatory Factor-1 in Dendritic Cells Restrains CD4+ T Cell Effector Responses and Induces CD25+Foxp3+ T Regulatory Subsets
nork: Diana M. Elizondo, et al.
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T-cell receptor repertoire usage after allografting differs between CD4+CD25+ regulatory T cells and their CD4+CD25− counterpart
nork: Claudio Fozza, et al.
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A brief in vitro activation is sufficient to equip naturally-occurring regulatory T Cells to control allograft rejection long-term
nork: Chan, T, et al.
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Exhaustive differentiation of alloreactive CD8+ T cells: critical for determination of graft acceptance or rejection.
nork: Steger, U, et al.
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Intravenous immunoglobulins promote skin allograft acceptance by triggering functional activation of CD4+Foxp3+ T cells.
nork: Tha-In, T, et al.
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B-Cell Depletion Improves Islet Allograft Survival with Anti-CD45RB
nork: Kang Mi Lee, et al.
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Single-Cell Landscape of Mouse Islet Allograft and Syngeneic Graft
nork: Pengfei Chen, et al.
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Correction: Expanded Human Regulatory T Cells Delay Islet Allograft Rejection via Inhibiting Islet-Derived Monocyte Chemoattractant Protein-1 Production in CD34 Stem Cells-Reconstituted NOD- Mice.
Argitaratua: (2014-01-01)

Pretransplant blood transfusion without additional immunotherapy generates CD25+CD4+ regulatory T cells: a potential explanation for the blood-transfusion effect.
nork: Bushell, A, et al.
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Galectin-1: a key effector of regulation mediated by CD4+CD25+ T cells.
nork: Garín, M, et al.
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Induction of transplantation tolerance converts potential effector T cells into graft-protective regulatory T cells.
nork: Francis, R, et al.
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CULTURED KERATINOCYTE GRAFTS ARE RECOGNIZED, BUT NOT REJECTED BY CD8+ T-CELLS INVIVO
nork: Tinois, E, et al.
Argitaratua: (1990)