2-methoxyestradiol inhibits hypoxia-inducible factor-1{alpha} and suppresses growth of lesions in a mouse model of endometriosis.

Endometriosis, the presence of ectopic endometrial tissue outside the uterine cavity, is a common disease affecting women during their reproductive years. Current therapeutic success is often unsatisfactory because of limited insight into disease mechanisms. Nevertheless, angiogenesis plays an essen...

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Бібліографічні деталі
Автори: Becker, C, Rohwer, N, Funakoshi, T, Cramer, T, Bernhardt, W, Birsner, A, Folkman, J, D'Amato, R
Формат: Journal article
Мова:English
Опубліковано: 2008