Glutamate carboxypeptidase II: a polymorphism associated with lower levels of serum folate and hyperhomocysteinemia.

Low blood folate levels result in hyperhomocysteinemia, which has been associated with increased risk for cardiovascular disease, neural tube defects and cognitive deficits. Intake of dietary folates is the chief determinant of blood folate levels. Molecular defects in the intestinal absorption of d...

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Bibliographic Details
Main Authors: Devlin, A, Ling, E, Peerson, J, Fernando, S, Clarke, R, Smith, A, Halsted, C
Format: Journal article
Language:English
Published: 2000