Manufacture and Mechanical Testing of Collagen Scaffold with Channels
Vascularization is considered as one of the current limitations in thick-tissue engineering. The design of the scaffolds with a network of channels is a promising approach to solve the problem of vascularization in thick artificial tissues. This paper presents a simple approach to make collagen scaf...
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| Format: | Conference item |
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2012
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| _version_ | 1797097802998743040 |
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| author | Du, X Czernuszka, J |
| author_facet | Du, X Czernuszka, J |
| author_sort | Du, X |
| collection | OXFORD |
| description | Vascularization is considered as one of the current limitations in thick-tissue engineering. The design of the scaffolds with a network of channels is a promising approach to solve the problem of vascularization in thick artificial tissues. This paper presents a simple approach to make collagen scaffolds with multi-channels by critical point drying and discusses how the channels influence the compressive properties of the scaffolds. The average diameter of the channels within scaffolds is 1.19±0.37mm. Due to the shrinkage of the scaffolds after drying, the relative densities of the scaffolds with different number of channels vary, which results in the difference of compression properties of scaffolds. © 2011 Springer-Verlag Berlin Heidelberg. |
| first_indexed | 2024-03-07T05:00:29Z |
| format | Conference item |
| id | oxford-uuid:d81a19a6-33ff-4342-b09b-e78903c30ee6 |
| institution | University of Oxford |
| last_indexed | 2024-03-07T05:00:29Z |
| publishDate | 2012 |
| record_format | dspace |
| spelling | oxford-uuid:d81a19a6-33ff-4342-b09b-e78903c30ee62022-03-27T08:45:54ZManufacture and Mechanical Testing of Collagen Scaffold with ChannelsConference itemhttp://purl.org/coar/resource_type/c_5794uuid:d81a19a6-33ff-4342-b09b-e78903c30ee6Symplectic Elements at Oxford2012Du, XCzernuszka, JVascularization is considered as one of the current limitations in thick-tissue engineering. The design of the scaffolds with a network of channels is a promising approach to solve the problem of vascularization in thick artificial tissues. This paper presents a simple approach to make collagen scaffolds with multi-channels by critical point drying and discusses how the channels influence the compressive properties of the scaffolds. The average diameter of the channels within scaffolds is 1.19±0.37mm. Due to the shrinkage of the scaffolds after drying, the relative densities of the scaffolds with different number of channels vary, which results in the difference of compression properties of scaffolds. © 2011 Springer-Verlag Berlin Heidelberg. |
| spellingShingle | Du, X Czernuszka, J Manufacture and Mechanical Testing of Collagen Scaffold with Channels |
| title | Manufacture and Mechanical Testing of Collagen Scaffold with Channels |
| title_full | Manufacture and Mechanical Testing of Collagen Scaffold with Channels |
| title_fullStr | Manufacture and Mechanical Testing of Collagen Scaffold with Channels |
| title_full_unstemmed | Manufacture and Mechanical Testing of Collagen Scaffold with Channels |
| title_short | Manufacture and Mechanical Testing of Collagen Scaffold with Channels |
| title_sort | manufacture and mechanical testing of collagen scaffold with channels |
| work_keys_str_mv | AT dux manufactureandmechanicaltestingofcollagenscaffoldwithchannels AT czernuszkaj manufactureandmechanicaltestingofcollagenscaffoldwithchannels |