Influence of irofulven, a transcription-coupled repair-specific antitumor agent, on RNA polymerase activity, stability and dynamics in living mammalian cells.

Influence of irofulven, a transcription-coupled repair-specific antitumor agent, on RNA polymerase activity, stability and dynamics in living mammalian cells.

Transcription-coupled repair (TCR) plays a key role in the repair of DNA lesions induced by bulky adducts and is initiated when the elongating RNA polymerase II (Pol II) stalls at DNA lesions. This is accompanied by alterations in Pol II activity and stability. We have previously shown that the mono...

Полное описание

Библиографические подробности
Главные авторы:	Escargueil, A, Poindessous, V, Soares, D, Sarasin, A, Cook, P, Larsen, A
Формат:	Journal article
Язык:	English
Опубликовано:	2008

Схожие документы

Enantioselective Total Synthesis of (−)-Acylfulvene and (−)- Irofulven
по: Movassaghi, Mohammad, и др.
Опубликовано: (2012)

Enantioselective total syntheses of acylfulvene, irofulven, and the agelastatins
по: Siegel, Dustin S. (Dustin Scott), 1980-
Опубликовано: (2011)

Different populations of RNA polymerase II in living mammalian cells.
по: Hieda, M, и др.
Опубликовано: (2005)

Different populations of RNA polymerase II in living mammalian cells
по: Cook, P, и др.
Опубликовано: (2005)

Transcriptional mutagenesis induced by 8-oxoguanine in mammalian cells.
по: Damien Brégeon, и др.
Опубликовано: (2009-07-01)

Coupled transcription and translation within nuclei of mammalian cells.
по: Iborra, F, и др.
Опубликовано: (2001)

The transcription cycle of RNA polymerase II in living cells
по: Kimura, H, и др.
Опубликовано: (2002)

The transcription cycle of RNA polymerase II in living cells.
по: Kimura, H, и др.
Опубликовано: (2002)

Coordination of transcription-coupled repair and repair-independent release of lesion-stalled RNA polymerase II
по: Yongchang Zhu, и др.
Опубликовано: (2024-08-01)

Molecular dissection of mammalian RNA polymerase II transcriptional termination.
по: West, S, и др.
Опубликовано: (2008)

The transcription-repair coupling factor Mfd associates with RNA polymerase in the absence of exogenous damage
по: Han N. Ho, и др.
Опубликовано: (2018-04-01)

Pause sites promote transcriptional termination of mammalian RNA polymerase II.
по: Gromak, N, и др.
Опубликовано: (2006)

Mechanism of Rad26-assisted rescue of stalled RNA polymerase II in transcription-coupled repair
по: Chunli Yan, и др.
Опубликовано: (2021-12-01)

The topology of transcription by immobilized polymerases.
по: Iborra, F, и др.
Опубликовано: (1996)

Fixing the model for transcription: the DNA moves, not the polymerase.
по: Papantonis, A, и др.
Опубликовано: (2011)

Monofunctional Platinum-DNA Adducts Are Strong Inhibitors of Transcription and Substrates for Nucleotide Excision Repair in Live Mammalian Cells
по: Zhu, Guangyu, и др.
Опубликовано: (2012)

Design and use of Chikungunya virus replication templates utilizing mammalian and mosquito RNA polymerase I mediated transcription
по: Utt, A, и др.
Опубликовано: (2019)

Transcription-Coupled Repair in Plants
по: Ana Lena Fidantsef, и др.
Опубликовано: (2012-01-01)

Transcription by an immobilized RNA polymerase from bacteriophage T7 and the topology of transcription.
по: Cook, P, и др.
Опубликовано: (1992)

Molecular cross-talk between the transcription, translation, and nonsense-mediated decay machineries.
по: Iborra, F, и др.
Опубликовано: (2004)

Specialized transcription factories within mammalian nuclei.
по: Pombo, A, и др.
Опубликовано: (2000)

Methylation of RNA polymerase II non-consensus Lysine residues marks early transcription in mammalian cells
по: João D Dias, и др.
Опубликовано: (2015-12-01)

Yeast and mammalian RNA polymerase II holoenzymes
по: Chao, David M. (David Min)
Опубликовано: (2008)

Mammalian DNA Polymerase Kappa Activity and Specificity
по: Hannah R. Stern, и др.
Опубликовано: (2019-08-01)

Does transcription by RNA polymerase play a direct role in the initiation of replication?
по: Hassan, A, и др.
Опубликовано: (1994)

Comparison of Commercially Available Thermostable DNA Polymerases with Reverse Transcriptase Activity in Coupled Reverse Transcription Polymerase Chain Reaction Assays
по: Evgeniya V. Smirnova, и др.
Опубликовано: (2025-01-01)

ACTIVE POLYMERASES FIXED IN REPLICATION AND TRANSCRIPTION FACTORIES
по: Hassan, B, и др.
Опубликовано: (1994)

Mammalian cell lines expressing functional RNA polymerase II tagged with the green fluorescent protein.
по: Sugaya, K, и др.
Опубликовано: (2000)

Measuring histone and polymerase dynamics in living cells.
по: Kimura, H, и др.
Опубликовано: (2004)

Transcription Inhibition by Platinum DNA Cross-links in Live Mammalian Cells
по: Ang, Wee Han, и др.
Опубликовано: (2011)

Time-resolved analysis of transcription kinetics in single live mammalian cells
по: Hongyoung Choi, и др.
Опубликовано: (2022-11-01)

A-MYB and BRDT-dependent RNA Polymerase II pause release orchestrates transcriptional regulation in mammalian meiosis
по: Adriana K. Alexander, и др.
Опубликовано: (2023-03-01)

Tyrosine phosphorylation of RNA polymerase II CTD is associated with antisense promoter transcription and active enhancers in mammalian cells
по: Nicolas Descostes, и др.
Опубликовано: (2014-05-01)

Correction: Rad26, the Transcription-Coupled Repair Factor in Yeast, Is Required for Removal of Stalled RNA Polymerase-II following UV Irradiation
Опубликовано: (2013-01-01)

Correction: Rad26, the Transcription-Coupled Repair Factor in Yeast, Is Required for Removal of Stalled RNA Polymerase-II following UV Irradiation.
по: Sounak Ghosh-Roy, и др.
Опубликовано: (2013-01-01)

DNA polymerase delta is required for early mammalian embryogenesis.
по: Arikuni Uchimura, и др.
Опубликовано: (2009-01-01)

The proteomes of transcription factories containing RNA polymerases I, II or III.
по: Melnik, S, и др.
Опубликовано: (2011)

Numbers and organization of RNA polymerases, nascent transcripts, and transcription units in HeLa nuclei.
по: Jackson, D, и др.
Опубликовано: (1998)

Numbers and organization of RNA polymerases, nascent transcripts, and transcription units in HeLa nuclei
по: Jackson, D, и др.
Опубликовано: (1998)

Biosurfactants as Potential Antitumor Agents
по: C. I., Ukaegbu, и др.
Опубликовано: (2023)