Differential clade-specific HLA-B*3501 association with HIV-1 disease outcome is linked to immunogenicity of a single Gag epitope.

The strongest genetic influence on immune control in HIV-1 infection is the HLA class I genotype. Rapid disease progression in B-clade infection has been linked to HLA-B*35 expression, in particular to the less common HLA-B*3502 and HLA-B*3503 subtypes but also to the most prevalent subtype, HLA-B*3...

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Main Authors: Matthews, P, Koyanagi, M, Kløverpris, H, Harndahl, M, Stryhn, A, Akahoshi, T, Gatanaga, H, Oka, S, Juarez Molina, C, Valenzuela Ponce, H, Avila Rios, S, Cole, D, Carlson, J, Payne, R, Ogwu, A, Bere, A, Ndung'u, T, Gounder, K, Chen, F, Riddell, L, Luzzi, G, Shapiro, R, Brander, C, Walker, B, Sewell, A
格式: Journal article
語言:English
出版: 2012