Selective Inhibition of Membrane Type 1 Matrix Metalloproteinase Abrogates Progression of Experimental Inflammatory Arthritis: Synergy With Tumor Necrosis Factor Blockade

In rheumatoid arthritis (RA), destruction of articular cartilage by the inflamed synovium is considered to be driven by increased activities of proteolytic enzymes, including matrix metalloproteinases (MMPs). The purpose of this study was to investigate the therapeutic potential of selective inhibit...

詳細記述

書誌詳細
主要な著者: Kaneko, K, Williams, R, Dransfield, D, Nixon, A, Sandison, A, Itoh, Y
フォーマット: Journal article
言語:English
出版事項: Wiley 2015