Seasonality of eosinophilic and non-eosinophilic exacerbations of COPD

Patients presenting with an exacerbation of COPD and a peripheral blood eosinophil count >=2% have a better response to oral cortico-steroids, suggesting that stratification by this biomarker identifies a pathologically distinct phenotype and might have clinical value.3 We have tested the hy...

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Bibliographic Details
Main Authors: Barker, R, Shrimanker, R, Russell, R, Fenton-Woods, J, Jones, C, Smith, L, Johnson, M, Pavord, I
Format: Journal article
Published: BMJ Publishing Group 2017
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Description
Summary:Patients presenting with an exacerbation of COPD and a peripheral blood eosinophil count >=2% have a better response to oral cortico-steroids, suggesting that stratification by this biomarker identifies a pathologically distinct phenotype and might have clinical value.3 We have tested the hypothesis that the eosinophilic and non-eosinophilicexacerbations of COPD have different seasonality using a large dataset of patents admitted to Kings College Hospital (KCH) with AECOPD over 10-years.