Modelling and analysis of LRRK2 mutations in iPSC-derived dopaminergic neurons and astrocytes

Modelling and analysis of LRRK2 mutations in iPSC-derived dopaminergic neurons and astrocytes

<p>Parkinson's disease (PD) is a common neurodegenerative disorder, characterised by preferential loss of ventral midbrain dopaminergic (vmDA) neurons in the substantia nigra pars compacta (SNc). The majority of PD cases have unknown aetiology; however, between 5-10% arise due to known ge...

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Dades bibliogràfiques
Autor principal:	Booth, H
Altres autors:	Wade-Martins, R
Format:	Thesis
Idioma:	English
Publicat:	2017

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