Modelling and analysis of LRRK2 mutations in iPSC-derived dopaminergic neurons and astrocytes

Modelling and analysis of LRRK2 mutations in iPSC-derived dopaminergic neurons and astrocytes

<p>Parkinson's disease (PD) is a common neurodegenerative disorder, characterised by preferential loss of ventral midbrain dopaminergic (vmDA) neurons in the substantia nigra pars compacta (SNc). The majority of PD cases have unknown aetiology; however, between 5-10% arise due to known ge...

書目詳細資料
主要作者:	Booth, H
其他作者:	Wade-Martins, R
格式:	Thesis
語言:	English
出版:	2017

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