The Drosophila homolog of MCPH1, a human microcephaly gene, is required for genomic stability in the early embryo
Mutation of human microcephalin (MCPH1) causes autosomal recessive primary microcephaly, a developmental disorder characterized by reduced brain size. We identified mcphl, the Drosophila homolog of MCPH1, in a genetic screen for regulators of S-M cycles in the early embryo. Embryos of null mcph1 fem...
Main Authors: | Rickmyre, J, DasGupta, S, Ooi, D, Keel, J, Lee, E, Kirschner, M, Waddell, S, Lee, L |
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Format: | Journal article |
Language: | English |
Published: |
2007
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