Lack of truncated IFITM3 transcripts in cells homozygous for the rs12252-C variant that is associated with severe influenza infection

Interferon-induced transmembrane 3 (IFITM3) is known to restrict the entry of a range of enveloped viruses. The single nucleotide polymorphism rs12252-C within IFITM3 has been shown to be associated with severe influenza A virus infection. It has been suggested that rs12252-C results in expression o...

Celý popis

Podrobná bibliografie
Hlavní autoři: Makvandi-Nejad, S, Laurenson-Schafer, H, Wang, L, Wellington, D, Zhao, Y, Jin, B, Qin, L, Kite, K, Moghadam, H, Song, C, Clark, K, Hublitz, P, Townsend, A, Wu, H, McMichael, A, Zhang, Y, Dong, T
Médium: Journal article
Jazyk:English
Vydáno: Oxford University Press 2017