Depletion of mitochondrial acyl carrier protein in bloodstream-form Trypanosoma brucei causes a kinetoplast segregation defect.

Depletion of mitochondrial acyl carrier protein in bloodstream-form Trypanosoma brucei causes a kinetoplast segregation defect.

Like other eukaryotes, trypanosomes have an essential type II fatty acid synthase in their mitochondrion. We have investigated the function of this synthase in bloodstream-form parasites by studying the effect of a conditional knockout of acyl carrier protein (ACP), a key player in this fatty acid s...

书目详细资料
Main Authors:	Clayton, A, Guler, J, Povelones, M, Gluenz, E, Gull, K, Smith, T, Jensen, R, Englund, P
格式:	Journal article
语言:	English
出版:	2011

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