Frequent use of IGHV3-30-3 in SARS-CoV-2 neutralizing antibody responses

The antibody response to SARS-CoV-2 shows biased immunoglobulin heavy chain variable (IGHV) gene usage, allowing definition of genetic signatures for some classes of neutralizing antibodies. We investigated IGHV gene usage frequencies by sorting spike-specific single memory B cells from individuals...

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Bibliographic Details
Main Authors: Pushparaj, P, Nicoletto, A, Castro Dopico, X, Sheward, DJ, Kim, S, Ekström, S, Murrell, B, Corcoran, M, Karlsson Hedestam, GB
Format: Journal article
Language:English
Published: Frontiers Media 2023