Synthesis and Crystal Structures of (RS,RS,RS)- and (1RS,2RS,3SR)-3-(N-Methylamino)cyclohexane-1,2-diol
3-(N-Methylamino)cyclohexane-1,2-diols (RS,RS,RS)-25 and (1RS,2RS,3SR)-26 were synthesised and their crystal structures were studied by X-ray diffraction. Compound 25 co-crystallizes with chloroform in the orthorhombic space group Pna2 1 with cell parameters of a = 11.8550(2) Å, b = 19.8293(4) Å, c...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2014
|
| _version_ | 1797097930668113920 |
|---|---|
| author | Davies, S Hewings, D Kurosawa, W Lee, J Roberts, P Thompson, A Thomson, J |
| author_facet | Davies, S Hewings, D Kurosawa, W Lee, J Roberts, P Thompson, A Thomson, J |
| author_sort | Davies, S |
| collection | OXFORD |
| description | 3-(N-Methylamino)cyclohexane-1,2-diols (RS,RS,RS)-25 and (1RS,2RS,3SR)-26 were synthesised and their crystal structures were studied by X-ray diffraction. Compound 25 co-crystallizes with chloroform in the orthorhombic space group Pna2 1 with cell parameters of a = 11.8550(2) Å, b = 19.8293(4) Å, c = 10.6163(2) Å, V = 2495.64(8) Å3 and Z = 8. Compound 26 crystallizes in the triclinic space group P-1 with cell parameters of a = 13.1019(3) Å, b = 15.0122(3) Å, c = 18.5562(5) Å, α = 95.3082(8), β = 90.3738(10), γ = 115.2775(9), V = 3281.87(14) Å3 and Z = 16. Both structures were characterised by arrays of hydrogen bonding interactions. Graphical Abstract: (RS,RS,RS)-3-(N-Methylamino)cyclohexane-1,2-diol and (1RS,2RS,3SR)-3-(N- Methylamino)cyclohexane-1,2-diol were synthesised and their structures were studied by X-ray diffraction.[Figure not available: see fulltext.] © 2013 Springer Science+Business Media New York. |
| first_indexed | 2024-03-07T05:02:21Z |
| format | Journal article |
| id | oxford-uuid:d8b9ae1b-3fe1-4b49-9a47-9031e52d245e |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:02:21Z |
| publishDate | 2014 |
| record_format | dspace |
| spelling | oxford-uuid:d8b9ae1b-3fe1-4b49-9a47-9031e52d245e2022-03-27T08:51:00ZSynthesis and Crystal Structures of (RS,RS,RS)- and (1RS,2RS,3SR)-3-(N-Methylamino)cyclohexane-1,2-diolJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d8b9ae1b-3fe1-4b49-9a47-9031e52d245eEnglishSymplectic Elements at Oxford2014Davies, SHewings, DKurosawa, WLee, JRoberts, PThompson, AThomson, J3-(N-Methylamino)cyclohexane-1,2-diols (RS,RS,RS)-25 and (1RS,2RS,3SR)-26 were synthesised and their crystal structures were studied by X-ray diffraction. Compound 25 co-crystallizes with chloroform in the orthorhombic space group Pna2 1 with cell parameters of a = 11.8550(2) Å, b = 19.8293(4) Å, c = 10.6163(2) Å, V = 2495.64(8) Å3 and Z = 8. Compound 26 crystallizes in the triclinic space group P-1 with cell parameters of a = 13.1019(3) Å, b = 15.0122(3) Å, c = 18.5562(5) Å, α = 95.3082(8), β = 90.3738(10), γ = 115.2775(9), V = 3281.87(14) Å3 and Z = 16. Both structures were characterised by arrays of hydrogen bonding interactions. Graphical Abstract: (RS,RS,RS)-3-(N-Methylamino)cyclohexane-1,2-diol and (1RS,2RS,3SR)-3-(N- Methylamino)cyclohexane-1,2-diol were synthesised and their structures were studied by X-ray diffraction.[Figure not available: see fulltext.] © 2013 Springer Science+Business Media New York. |
| spellingShingle | Davies, S Hewings, D Kurosawa, W Lee, J Roberts, P Thompson, A Thomson, J Synthesis and Crystal Structures of (RS,RS,RS)- and (1RS,2RS,3SR)-3-(N-Methylamino)cyclohexane-1,2-diol |
| title | Synthesis and Crystal Structures of (RS,RS,RS)- and (1RS,2RS,3SR)-3-(N-Methylamino)cyclohexane-1,2-diol |
| title_full | Synthesis and Crystal Structures of (RS,RS,RS)- and (1RS,2RS,3SR)-3-(N-Methylamino)cyclohexane-1,2-diol |
| title_fullStr | Synthesis and Crystal Structures of (RS,RS,RS)- and (1RS,2RS,3SR)-3-(N-Methylamino)cyclohexane-1,2-diol |
| title_full_unstemmed | Synthesis and Crystal Structures of (RS,RS,RS)- and (1RS,2RS,3SR)-3-(N-Methylamino)cyclohexane-1,2-diol |
| title_short | Synthesis and Crystal Structures of (RS,RS,RS)- and (1RS,2RS,3SR)-3-(N-Methylamino)cyclohexane-1,2-diol |
| title_sort | synthesis and crystal structures of rs rs rs and 1rs 2rs 3sr 3 n methylamino cyclohexane 1 2 diol |
| work_keys_str_mv | AT daviess synthesisandcrystalstructuresofrsrsrsand1rs2rs3sr3nmethylaminocyclohexane12diol AT hewingsd synthesisandcrystalstructuresofrsrsrsand1rs2rs3sr3nmethylaminocyclohexane12diol AT kurosawaw synthesisandcrystalstructuresofrsrsrsand1rs2rs3sr3nmethylaminocyclohexane12diol AT leej synthesisandcrystalstructuresofrsrsrsand1rs2rs3sr3nmethylaminocyclohexane12diol AT robertsp synthesisandcrystalstructuresofrsrsrsand1rs2rs3sr3nmethylaminocyclohexane12diol AT thompsona synthesisandcrystalstructuresofrsrsrsand1rs2rs3sr3nmethylaminocyclohexane12diol AT thomsonj synthesisandcrystalstructuresofrsrsrsand1rs2rs3sr3nmethylaminocyclohexane12diol |