MDC1 interacts with TOPBP1 to maintain chromosomal stability during Mitosis

MDC1 interacts with TOPBP1 to maintain chromosomal stability during Mitosis

In mitosis, cells inactivate DNA double-strand break (DSB) repair pathways to preserve genome stability. However, some early signaling events still occur, such as recruitment of the scaffold protein MDC1 to phosphorylated histone H2AX at DSBs. Yet, it remains unclear whether these events are importa...

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Príomhchruthaitheoirí:	Leimbacher, P-A, Jones, SE, Shorrocks, A-MK, De Marco Zompit, M, Day, M, Blaauwendraad, J, Bundschuh, D, Bonham, S, Fischer, R, Fink, D, Kessler, BM, Oliver, AW, Pearl, LH, Blackford, AN, Stucki, M
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	Elsevier 2019

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