Molecular approaches to epidemiology and clinical aspects of malaria.

Malaria is a problem of global importance, responsible for 1-2 million deaths per year, mainly in African children, as well as considerable morbidity manifested as severe anaemia and encephalopathy in young children. Fundamental to the development of new tools for malaria control in humans is an inc...

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Main Authors: Brown, G, Beck, H, Molyneux, M, Marsh, K
Format: Journal article
Language:English
Published: 2000
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author Brown, G
Beck, H
Molyneux, M
Marsh, K
author_facet Brown, G
Beck, H
Molyneux, M
Marsh, K
author_sort Brown, G
collection OXFORD
description Malaria is a problem of global importance, responsible for 1-2 million deaths per year, mainly in African children, as well as considerable morbidity manifested as severe anaemia and encephalopathy in young children. Fundamental to the development of new tools for malaria control in humans is an increased understanding of key features of malaria infection, such as the diversity of outcome in different individuals, the understanding of different manifestations of the disease and of the mechanisms of immunity that allow clinical protection in the face of ongoing low-grade infection (concomitant immunity or premunition). Here, Graham Brown and colleagues review some of the ways in which molecular approaches might be used to increase our understanding of the epidemiology and clinical manifestations of malaria, as discussed at the Molecular Approaches to Malaria conference (MAM2000), Lorne, Australia, 2-5 February 2000.
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spelling oxford-uuid:d8fda7f3-f265-4ee2-ac9b-599f620faec52022-03-27T08:52:41ZMolecular approaches to epidemiology and clinical aspects of malaria.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d8fda7f3-f265-4ee2-ac9b-599f620faec5EnglishSymplectic Elements at Oxford2000Brown, GBeck, HMolyneux, MMarsh, KMalaria is a problem of global importance, responsible for 1-2 million deaths per year, mainly in African children, as well as considerable morbidity manifested as severe anaemia and encephalopathy in young children. Fundamental to the development of new tools for malaria control in humans is an increased understanding of key features of malaria infection, such as the diversity of outcome in different individuals, the understanding of different manifestations of the disease and of the mechanisms of immunity that allow clinical protection in the face of ongoing low-grade infection (concomitant immunity or premunition). Here, Graham Brown and colleagues review some of the ways in which molecular approaches might be used to increase our understanding of the epidemiology and clinical manifestations of malaria, as discussed at the Molecular Approaches to Malaria conference (MAM2000), Lorne, Australia, 2-5 February 2000.
spellingShingle Brown, G
Beck, H
Molyneux, M
Marsh, K
Molecular approaches to epidemiology and clinical aspects of malaria.
title Molecular approaches to epidemiology and clinical aspects of malaria.
title_full Molecular approaches to epidemiology and clinical aspects of malaria.
title_fullStr Molecular approaches to epidemiology and clinical aspects of malaria.
title_full_unstemmed Molecular approaches to epidemiology and clinical aspects of malaria.
title_short Molecular approaches to epidemiology and clinical aspects of malaria.
title_sort molecular approaches to epidemiology and clinical aspects of malaria
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