The activities of various antimalarial drugs on Plasmodium falciparum isolates in Kilifi Kenya and studies on mechanisms of resistance

The activities of various antimalarial drugs on Plasmodium falciparum isolates in Kilifi Kenya and studies on mechanisms of resistance

<p>Drug resistance is a significant challenge in the fight against malaria. Importantly, reduced efficacy has been reported against artemether (ATM)/Lumefantrine (LM) (LM-ATM), amodiaquine (AQ)/artesunate (AS) (AQ-AS), two important combination treatment regimens in Africa, and against piperaq...

Полное описание

Библиографические подробности
Главный автор:	Mwai, L
Другие авторы:	Marsh, K
Формат:	Диссертация
Язык:	English
Опубликовано:	2011
Предметы:	Clinical laboratory sciences Clinical microbiology Malaria Pharmacology Medical Sciences Biology Multidrug resistance Genetics (life sciences) Parasitology Public Health Genetics (medical sciences) Tropical medicine Infectious diseases Life Sciences Bioinformatics (life sciences)

Схожие документы

Identifying genetic determinants of impaired PfEMP1 export in Plasmodium falciparum-infected erythrocytes
по: Neal, AT
Опубликовано: (2014)

Within-host evolution of HIV-1 and the analysis of transmissible diversity
по: English, SE
Опубликовано: (2012)

Reproducing speech intervals in the sub-hundred millisecond (ms) range with a translocation in 7q31
по: Garcia-Bellido, P
Опубликовано: (2013)

Study of platelet-mediated clumping adhesion phenotypes in Plasmodium falciparum malaria
по: Onyambu, F, и др.
Опубликовано: (2015)

Accessing complex genomic variation in Plasmodium falciparum natural infections
по: Wendler, J
Опубликовано: (2015)

Identifying causative elements within structural variants associated with developmental disorders
по: Boulding, H
Опубликовано: (2013)

An analysis of non-coding RNAs in Plasmodium falciparum and their potential role in antigenic variation
по: Christodoulou, Z
Опубликовано: (2012)

Identification of novel genes involved in brain abnormality syndromes using next generation sequencing
по: Howard, M, и др.
Опубликовано: (2014)

Functional genomics of severe sepsis and septic shock
по: Radhakrishnan, J
Опубликовано: (2013)

Pathogenic mycobacteria achieve cellular persistence via lipid-mediated inhibition of the Niemann-Pick disease type C pathway
по: Fineran, PD
Опубликовано: (2014)

A method for the identification of biological pathways
по: Honti, F
Опубликовано: (2014)

Cortical dynamics subserving visual apparent motion
по: Ahmed, B, и др.
Опубликовано: (2008)

The haptoglobin 2-2 genotype is associated with a reduced incidence of Plasmodium falciparum malaria in children on the coast of Kenya
по: Atkinson, S, и др.
Опубликовано: (2007)

Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma
по: Taylor, K, и др.
Опубликовано: (2014)

The roles of the homeobox genes ALX4 and MSX2 in skull development
по: Mavrogiannis, L
Опубликовано: (2004)

Enhancing the efficacy of viral vector blood-stage malaria vaccines
по: Forbes, E
Опубликовано: (2011)

Morbidity and mortality due to Plasmodium vivax malaria in Papua, Indonesia and its control using antimalarial drugs
по: Douglas, N
Опубликовано: (2011)

The genetics of handedness and dyslexia
по: Brandler, W
Опубликовано: (2014)

Evaluation of strain circulation and the epidemiology of enteric fever caused
по: Karkey, A, и др.
Опубликовано: (2012)

The clinical significance of cerebrospinal fluid levels of kynurenine pathway metabolites and lactate in severe malaria
по: Medana, I, и др.
Опубликовано: (2002)

Lactate levels in severe malarial anaemia are associated with haemozoin-containing neutrophils and low levels of IL-12
по: Casals-Pascual, C, и др.
Опубликовано: (2006)

Revisiting the design of phase III clinical trials of antimalarial drugs for uncomplicated Plasmodium falciparum malaria
по: Borrmann, S, и др.
Опубликовано: (2008)

Intergenic long noncoding RNAs provide a novel layer of post-transcriptional regulation in development and disease
по: Tan, J
Опубликовано: (2014)

Genetics of chronic otitis media: a mouse to man approach
по: Bhutta, M
Опубликовано: (2012)

Probing the molecular basis of melanopsin induced light sensitivity
по: Vachtsevanos, AN
Опубликовано: (2012)

Survival and haematological recovery of children with severe malaria transfused in accordance to WHO guidelines in Kilifi, Kenya
по: Akech, S, и др.
Опубликовано: (2008)

Examining the relationship between genetic variation at G6PD and severe malaria
по: Shah, SS
Опубликовано: (2011)

Clinical studies on enteric fever
по: Arjyal, A, и др.
Опубликовано: (2014)

Prevalence of Staphylococcus aureus protein A (spa) mutants in the community and hospitals in Oxfordshire.
по: Votintseva, A, и др.
Опубликовано: (2014)

On genetic variants underlying common disease
по: Hechter, E
Опубликовано: (2011)

The analysis of homologous recombination pathways in Saccharomyces Cerevisiae
по: Tay, Y
Опубликовано: (2010)

Elucidating the input of notch ligand delta-like 4 (dll4) in zebrafish blood stem cell ontogeny
по: Schneider, J, и др.
Опубликовано: (2014)

A high-order trans-membrane structural linkage is responsible for mitochondrial genome positioning and segregation by flagellar basal bodies in trypanosomes
по: Ogbadoyi, E, и др.
Опубликовано: (2003)

Functional characterisation of a multiple sclerosis-associated genetic variant
по: Gregory, A
Опубликовано: (2012)

Molecular mechanisms of recombination hotspots in humans
по: Noor, N
Опубликовано: (2013)

Whole-genome analysis of the transcriptional network underlying male sexual behaviour in Drosophila melanogaster
по: Ashley, E, и др.
Опубликовано: (2012)

Human population structure and demographic history using genetic markers
по: Wilson, J, и др.
Опубликовано: (2002)

Germline determinants of 5-fluorouracil drug toxicity and patient survival in colorectal cancer
по: Rosmarin, DN
Опубликовано: (2013)

Pathogen identification in lower respiratory tract infection
по: Wrightson, JM
Опубликовано: (2014)

Human genetic resistance to malaria.
по: Williams, T
Опубликовано: (2009)