Dissecting the role of CBP/P300-mediated acetylation in enhancer function
<p>Enhancers are major determinants of tissue-specific gene expression. Although it is not entirely clear how enhancers activate target genes, nucleosomes at enhancers tend to have high levels of H3K27ac, which is deposited by the lysine acetyltransferases (KATs) CBP and P300. However, the ext...
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| Format: | Thesis |
| Jezik: | English |
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2023
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