Enrichment of low penetrance susceptibility loci in a Dutch familial colorectal cancer cohort.

Enrichment of low penetrance susceptibility loci in a Dutch familial colorectal cancer cohort.

Recent genome-wide association studies have identified several loci that confer an increased risk of colorectal cancer (CRC). We studied the role of the 8q24.21 (rs6983267), 18q21.1 (rs12953717), 15q13.3 (rs4779584), 11q23.1 (rs3802842), 8q23.3 (rs16892766), and 10p14 (rs10795668) risk variants in a...

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Détails bibliographiques
Auteurs principaux:	Middeldorp, A, Jagmohan-Changur, S, van Eijk, R, Tops, C, Devilee, P, Vasen, H, Hes, F, Houlston, R, Tomlinson, I, Houwing-Duistermaat, J, Wijnen, J, Morreau, H, van Wezel, T
Format:	Journal article
Langue:	English
Publié:	2009

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