Calcium and inositolphosphates in the activation of T cell-mediated cytotoxicity.

Reports from a number of laboratories have shown that mAbs against the T3-Ti receptor complex cause an increase in cytosolic-free Ca2+ [( Ca2+]i) and the hydrolysis of phosphatidylinositolbisphosphate (PIP2) in CTLs. In the present report we show that activation of CTLs by their specific targets cau...

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Những tác giả chính: Treves, S, Di Virgilio, F, Cerundolo, V, Zanovello, P, Collavo, D, Pozzan, T
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 1987