The role of mathematical modelling in guiding the science and economics of malaria elimination
<p style="text-align:justify;"> Unprecedented efforts are now underway to eliminate malaria from many regions. Despite the enormous financial resources committed, if malaria elimination is perceived as failing it is likely that this funding will not be sustained. It is imperative th...
Autors principals: | , , , , , , , , , |
---|---|
Format: | Journal article |
Idioma: | English |
Publicat: |
Oxford University Press
2010
|
_version_ | 1826299578266157056 |
---|---|
author | Maude, R Lubell, Y Socheat, D Yeung, S Saralamba, S Pongtavornpinyo, W Cooper, B Dondorp, A White, N White, L |
author_facet | Maude, R Lubell, Y Socheat, D Yeung, S Saralamba, S Pongtavornpinyo, W Cooper, B Dondorp, A White, N White, L |
author_sort | Maude, R |
collection | OXFORD |
description | <p style="text-align:justify;"> Unprecedented efforts are now underway to eliminate malaria from many regions. Despite the enormous financial resources committed, if malaria elimination is perceived as failing it is likely that this funding will not be sustained. It is imperative that methods are developed to use the limited data available to design site-specific, cost-effective elimination programmes. Mathematical modelling is a way of including mechanistic understanding to use available data to make predictions. Different strategies can be evaluated much more rapidly than is possible through trial and error in the field. Mathematical modelling has great potential as a tool to guide and inform current elimination efforts. Economic modelling weighs costs against characterised effects or predicted benefits in order to determine the most cost-efficient strategy but has traditionally used static models of disease not suitable for elimination. Dynamic mathematical modelling and economic modelling techniques need to be combined to contribute most effectively to ongoing policy discussions. We review the role of modelling in previous malaria control efforts as well as the unique nature of elimination and the consequent need for its explicit modelling, and emphasise the importance of good disease surveillance. The difficulties and complexities of economic evaluation of malaria control, particularly the end stages of elimination, are discussed. </p> |
first_indexed | 2024-03-07T05:04:03Z |
format | Journal article |
id | oxford-uuid:d94e157c-1d22-4c41-8b9a-e80f1db45adc |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T05:04:03Z |
publishDate | 2010 |
publisher | Oxford University Press |
record_format | dspace |
spelling | oxford-uuid:d94e157c-1d22-4c41-8b9a-e80f1db45adc2022-03-27T08:54:57ZThe role of mathematical modelling in guiding the science and economics of malaria eliminationJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d94e157c-1d22-4c41-8b9a-e80f1db45adcEnglishSymplectic Elements at OxfordOxford University Press2010Maude, RLubell, YSocheat, DYeung, SSaralamba, SPongtavornpinyo, WCooper, BDondorp, AWhite, NWhite, L <p style="text-align:justify;"> Unprecedented efforts are now underway to eliminate malaria from many regions. Despite the enormous financial resources committed, if malaria elimination is perceived as failing it is likely that this funding will not be sustained. It is imperative that methods are developed to use the limited data available to design site-specific, cost-effective elimination programmes. Mathematical modelling is a way of including mechanistic understanding to use available data to make predictions. Different strategies can be evaluated much more rapidly than is possible through trial and error in the field. Mathematical modelling has great potential as a tool to guide and inform current elimination efforts. Economic modelling weighs costs against characterised effects or predicted benefits in order to determine the most cost-efficient strategy but has traditionally used static models of disease not suitable for elimination. Dynamic mathematical modelling and economic modelling techniques need to be combined to contribute most effectively to ongoing policy discussions. We review the role of modelling in previous malaria control efforts as well as the unique nature of elimination and the consequent need for its explicit modelling, and emphasise the importance of good disease surveillance. The difficulties and complexities of economic evaluation of malaria control, particularly the end stages of elimination, are discussed. </p> |
spellingShingle | Maude, R Lubell, Y Socheat, D Yeung, S Saralamba, S Pongtavornpinyo, W Cooper, B Dondorp, A White, N White, L The role of mathematical modelling in guiding the science and economics of malaria elimination |
title | The role of mathematical modelling in guiding the science and economics of malaria elimination |
title_full | The role of mathematical modelling in guiding the science and economics of malaria elimination |
title_fullStr | The role of mathematical modelling in guiding the science and economics of malaria elimination |
title_full_unstemmed | The role of mathematical modelling in guiding the science and economics of malaria elimination |
title_short | The role of mathematical modelling in guiding the science and economics of malaria elimination |
title_sort | role of mathematical modelling in guiding the science and economics of malaria elimination |
work_keys_str_mv | AT mauder theroleofmathematicalmodellinginguidingthescienceandeconomicsofmalariaelimination AT lubelly theroleofmathematicalmodellinginguidingthescienceandeconomicsofmalariaelimination AT socheatd theroleofmathematicalmodellinginguidingthescienceandeconomicsofmalariaelimination AT yeungs theroleofmathematicalmodellinginguidingthescienceandeconomicsofmalariaelimination AT saralambas theroleofmathematicalmodellinginguidingthescienceandeconomicsofmalariaelimination AT pongtavornpinyow theroleofmathematicalmodellinginguidingthescienceandeconomicsofmalariaelimination AT cooperb theroleofmathematicalmodellinginguidingthescienceandeconomicsofmalariaelimination AT dondorpa theroleofmathematicalmodellinginguidingthescienceandeconomicsofmalariaelimination AT whiten theroleofmathematicalmodellinginguidingthescienceandeconomicsofmalariaelimination AT whitel theroleofmathematicalmodellinginguidingthescienceandeconomicsofmalariaelimination AT mauder roleofmathematicalmodellinginguidingthescienceandeconomicsofmalariaelimination AT lubelly roleofmathematicalmodellinginguidingthescienceandeconomicsofmalariaelimination AT socheatd roleofmathematicalmodellinginguidingthescienceandeconomicsofmalariaelimination AT yeungs roleofmathematicalmodellinginguidingthescienceandeconomicsofmalariaelimination AT saralambas roleofmathematicalmodellinginguidingthescienceandeconomicsofmalariaelimination AT pongtavornpinyow roleofmathematicalmodellinginguidingthescienceandeconomicsofmalariaelimination AT cooperb roleofmathematicalmodellinginguidingthescienceandeconomicsofmalariaelimination AT dondorpa roleofmathematicalmodellinginguidingthescienceandeconomicsofmalariaelimination AT whiten roleofmathematicalmodellinginguidingthescienceandeconomicsofmalariaelimination AT whitel roleofmathematicalmodellinginguidingthescienceandeconomicsofmalariaelimination |