The role of mathematical modelling in guiding the science and economics of malaria elimination

<p style="text-align:justify;"> Unprecedented efforts are now underway to eliminate malaria from many regions. Despite the enormous financial resources committed, if malaria elimination is perceived as failing it is likely that this funding will not be sustained. It is imperative th...

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Autors principals: Maude, R, Lubell, Y, Socheat, D, Yeung, S, Saralamba, S, Pongtavornpinyo, W, Cooper, B, Dondorp, A, White, N, White, L
Format: Journal article
Idioma:English
Publicat: Oxford University Press 2010
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author Maude, R
Lubell, Y
Socheat, D
Yeung, S
Saralamba, S
Pongtavornpinyo, W
Cooper, B
Dondorp, A
White, N
White, L
author_facet Maude, R
Lubell, Y
Socheat, D
Yeung, S
Saralamba, S
Pongtavornpinyo, W
Cooper, B
Dondorp, A
White, N
White, L
author_sort Maude, R
collection OXFORD
description <p style="text-align:justify;"> Unprecedented efforts are now underway to eliminate malaria from many regions. Despite the enormous financial resources committed, if malaria elimination is perceived as failing it is likely that this funding will not be sustained. It is imperative that methods are developed to use the limited data available to design site-specific, cost-effective elimination programmes. Mathematical modelling is a way of including mechanistic understanding to use available data to make predictions. Different strategies can be evaluated much more rapidly than is possible through trial and error in the field. Mathematical modelling has great potential as a tool to guide and inform current elimination efforts. Economic modelling weighs costs against characterised effects or predicted benefits in order to determine the most cost-efficient strategy but has traditionally used static models of disease not suitable for elimination. Dynamic mathematical modelling and economic modelling techniques need to be combined to contribute most effectively to ongoing policy discussions. We review the role of modelling in previous malaria control efforts as well as the unique nature of elimination and the consequent need for its explicit modelling, and emphasise the importance of good disease surveillance. The difficulties and complexities of economic evaluation of malaria control, particularly the end stages of elimination, are discussed. </p>
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spelling oxford-uuid:d94e157c-1d22-4c41-8b9a-e80f1db45adc2022-03-27T08:54:57ZThe role of mathematical modelling in guiding the science and economics of malaria eliminationJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d94e157c-1d22-4c41-8b9a-e80f1db45adcEnglishSymplectic Elements at OxfordOxford University Press2010Maude, RLubell, YSocheat, DYeung, SSaralamba, SPongtavornpinyo, WCooper, BDondorp, AWhite, NWhite, L <p style="text-align:justify;"> Unprecedented efforts are now underway to eliminate malaria from many regions. Despite the enormous financial resources committed, if malaria elimination is perceived as failing it is likely that this funding will not be sustained. It is imperative that methods are developed to use the limited data available to design site-specific, cost-effective elimination programmes. Mathematical modelling is a way of including mechanistic understanding to use available data to make predictions. Different strategies can be evaluated much more rapidly than is possible through trial and error in the field. Mathematical modelling has great potential as a tool to guide and inform current elimination efforts. Economic modelling weighs costs against characterised effects or predicted benefits in order to determine the most cost-efficient strategy but has traditionally used static models of disease not suitable for elimination. Dynamic mathematical modelling and economic modelling techniques need to be combined to contribute most effectively to ongoing policy discussions. We review the role of modelling in previous malaria control efforts as well as the unique nature of elimination and the consequent need for its explicit modelling, and emphasise the importance of good disease surveillance. The difficulties and complexities of economic evaluation of malaria control, particularly the end stages of elimination, are discussed. </p>
spellingShingle Maude, R
Lubell, Y
Socheat, D
Yeung, S
Saralamba, S
Pongtavornpinyo, W
Cooper, B
Dondorp, A
White, N
White, L
The role of mathematical modelling in guiding the science and economics of malaria elimination
title The role of mathematical modelling in guiding the science and economics of malaria elimination
title_full The role of mathematical modelling in guiding the science and economics of malaria elimination
title_fullStr The role of mathematical modelling in guiding the science and economics of malaria elimination
title_full_unstemmed The role of mathematical modelling in guiding the science and economics of malaria elimination
title_short The role of mathematical modelling in guiding the science and economics of malaria elimination
title_sort role of mathematical modelling in guiding the science and economics of malaria elimination
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