Molecular dynamics simulations of inwardly rectifying (Kir) potassium channels: a comparative study.

Molecular dynamics simulations of inwardly rectifying (Kir) potassium channels: a comparative study.

Inward rectifier potassium (Kir) channels regulate cell excitability and transport K+ ions across membranes. Homotetrameric models of three mammalian Kir channels (Kir1.1, Kir3.1, and Kir6.2) have been generated, using the KirBac3.1 transmembrane and rat Kir3.1 intracellular domain structures as tem...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Haider, S, Khalid, S, Tucker, S, Ashcroft, F, Sansom, MS
Format:	Journal article
Sprache:	English
Veröffentlicht:	2007

Ähnliche Einträge

Conformational dynamics of the ligand-binding domain of inward rectifier K channels as revealed by molecular dynamics simulations: toward an understanding of Kir channel gating.
von: Haider, S, et al.
Veröffentlicht: (2005)

Mapping of the physical interaction between the intracellular domains of an inwardly rectifying potassium channel, Kir6.2.
von: Tucker, S, et al.
Veröffentlicht: (1999)

Endocannabinoid regulation of inward rectifier potassium (Kir) channels
von: Sultan Mayar, et al.
Veröffentlicht: (2024-08-01)

Phosphoinositide Regulation of Inward Rectifier Potassium (Kir) Channels
von: Oliver eFurst, et al.
Veröffentlicht: (2014-01-01)

Multiple sites of interaction between the intracellular domains of an inwardly rectifying potassium channel, Kir6.2.
von: Jones, P, et al.
Veröffentlicht: (2001)

Inwardly rectifying potassium channels.
von: Reimann, F, et al.
Veröffentlicht: (1999)

Computer modelling and simulation studies of a human inwardly rectifying potassium channel Kir6.2
von: Capener, C, et al.
Veröffentlicht: (2000)

Homology modeling and molecular dynamics simulation studies of an inward rectifier potassium channel.
von: Capener, C, et al.
Veröffentlicht: (2000)

Defining how multiple lipid species interact with inward rectifier potassium (Kir2) channels
von: Duncan, AL, et al.
Veröffentlicht: (2020)

Nuance of inward rectifying potassium (Kir) channel dysfunctions in neurodegenerative diseases
von: Benjamin Garland, et al.
Veröffentlicht: (2024-01-01)

Role of Astrocytic Inwardly Rectifying Potassium (Kir) 4.1 Channels in Epileptogenesis
von: Masato Kinboshi, et al.
Veröffentlicht: (2020-12-01)

Filter flexibility and distortion in a bacterial inward rectifier K+ channel: simulation studies of KirBac1.1.
von: Domene, C, et al.
Veröffentlicht: (2004)

pH dependence of the inwardly rectifying potassium channel, Kir5.1, and localization in renal tubular epithelia.
von: Tucker, S, et al.
Veröffentlicht: (2000)

Involvement of Inwardly Rectifying Potassium (Kir) Channels in the Toxicity of Flonicamid to <i>Drosophila melanogaster</i>
von: Xuan Liu, et al.
Veröffentlicht: (2025-01-01)

Cloning, functional expression, and pharmacological characterization of inwardly rectifying potassium channels (Kir) from Apis mellifera
von: Fabien Sourisseau, et al.
Veröffentlicht: (2024-04-01)

Diverse functions of the inward-rectifying potassium channel Kir5.1 and its relationship with human diseases
von: Chaojie Zhang, et al.
Veröffentlicht: (2023-02-01)

Promiscuous coupling between the sulphonylurea receptor and inwardly rectifying potassium channels.
von: Ammälä, C, et al.
Veröffentlicht: (1996)

Discovery, characterization and structure-activity relationships of an inhibitor of inward rectifier potassium (Kir) channels with preference for Kir2.3, Kir3.X and Kir7.1
von: Jerod S Denton
Veröffentlicht: (2011-11-01)

Pharmacological validation of an inward-rectifier potassium (Kir) channel as an insecticide target in the yellow fever mosquito Aedes aegypti.
von: Matthew F Rouhier, et al.
Veröffentlicht: (2014-01-01)

INWARDLY RECTIFYING K+ CURRENTS IN OOCYTES CO-EXPRESSING KIR3.1 AND KIR3.2
von: Ammala, C, et al.
Veröffentlicht: (1995)

Epsilon Toxin from <i>Clostridium perfringens</i> Causes Inhibition of Potassium inward Rectifier (Kir) Channels in Oligodendrocytes
von: Jean Louis Bossu, et al.
Veröffentlicht: (2020-01-01)

Cloning and functional characterization of a superfamily of microbial inwardly rectifying potassium channels.
von: Sun, S, et al.
Veröffentlicht: (2006)

Two types of gating in inward rectifiers: The case of the K-ATP channel.
von: Proks, P, et al.
Veröffentlicht: (2001)

Inhibition of Inwardly Rectifying Potassium (Kir) 4.1 Channels Facilitates Brain-Derived Neurotrophic Factor (BDNF) Expression in Astrocytes
von: Masato Kinboshi, et al.
Veröffentlicht: (2017-12-01)

Inward rectifier potassium (Kir) channels mediate salivary gland function and blood feeding in the lone star tick, Amblyomma americanum.
von: Zhilin Li, et al.
Veröffentlicht: (2019-02-01)

Focus on Kir6.2: a key component of the ATP-sensitive potassium channel.
von: Haider, S, et al.
Veröffentlicht: (2005)

Advancements in the study of inward rectifying potassium channels on vascular cells
von: Chunshu Li, et al.
Veröffentlicht: (2023-12-01)

The sulphonylurea receptor confers diazoxide sensitivity on the inwardly rectifying K+ channel Kir6.1 expressed in human embryonic kidney cells.
von: Ammälä, C, et al.
Veröffentlicht: (1996)

The inwardly rectifying K+ channel KIR7.1 controls uterine excitability throughout pregnancy.
von: McCloskey, C, et al.
Veröffentlicht: (2014)

The inwardly rectifying K+ channel KIR7.1 controls uterine excitability throughout pregnancy
von: Conor McCloskey, et al.
Veröffentlicht: (2014-07-01)

ATP-dependent interaction of the cytosolic domains of the inwardly rectifying K+ channel Kir6.2 revealed by fluorescence resonance energy transfer.
von: Tsuboi, T, et al.
Veröffentlicht: (2004)

CHARACTERIZATION OF AN INWARDLY RECTIFYING K+ CHANNEL EXPRESSED IN PANCREATIC BETA-CELLS
von: Ashcroft, F
Veröffentlicht: (1995)

Identification and distribution of inwardly rectifying potassium channels in rat microvascular endothelial cells
von: Hinton, J, et al.
Veröffentlicht: (2000)

Identification and distribution of inwardly rectifying potassium channels in rat microvascular endothelial cells
von: Hinton, J, et al.
Veröffentlicht: (2000)

Direct modulation of G protein-gated inwardly rectifying potassium (GIRK) channels
von: Ha Nguyen, et al.
Veröffentlicht: (2024-06-01)

From in silico to in vitro: a trip to reveal flavonoid binding on the Rattus norvegicus Kir6.1 ATP-sensitive inward rectifier potassium channel
von: Alfonso Trezza, et al.
Veröffentlicht: (2018-05-01)

Differential expression of the inwardly-rectifying K-channel ROMK1 in rat brain.
von: Kenna, S, et al.
Veröffentlicht: (1994)

Characterization of the chicken inward rectifier K<sup>+ </sup>channel <it>IRK1/Kir2.1 </it>gene
von: Locke Emily, et al.
Veröffentlicht: (2004-11-01)

H bonding at the helix-bundle crossing controls gating in Kir potassium channels.
von: Rapedius, M, et al.
Veröffentlicht: (2007)

Inwardly rectifying potassium channels in rat hepatic artery endothelial and smooth muscle cells.
von: Walker, S, et al.
Veröffentlicht: (2000)