Azasugar analogues: conformationally restricted vicinal diamine derived from (S)-(-)-pyroglutamic acid

Azasugar analogues: conformationally restricted vicinal diamine derived from (S)-(-)-pyroglutamic acid

The preparation of a diamino substituted pyrrolidinone system in a diastereoselectively controlled manner is described. The procedure employed made use of electrophilic amination of a chiral bicyclic γ-lactam, which when subjected to sequential deprotection provided a simple route to a 3,4- diaminop...

书目详细资料
Main Authors:	Chan, P, Cottrell, I, Moloney, M
格式:	Journal article
语言:	English
出版:	1999

相似书籍

Pyrrolidinones derived from (S)-pyroglutamic acid. Part 2. Conformationally constrained kainoid analogues
由: Dyer, J, et al.
出版: (2000)

Pyrrolidinones derived from (S)-pyroglutamic acid. Part 3. beta-aminopyrrolidinones
由: Chan, P, et al.
出版: (2001)

Stereoselective synthesis of conformationally constrained omega-amino acid analogues from pyroglutamic acid.
由: Bentz, E, et al.
出版: (2005)

Pyrrolidinones derived from (S)-pyroglutamic acid: penmacric acid and analogues.
由: Anwar, M, et al.
出版: (2003)

Pyrrolidinones derived from (S)-pyroglutamic acid. Part 4. alpha,beta-diaminopyrrolidinones
由: Chan, P, et al.
出版: (2001)

Novel peptidomimetic structures: enantioselective synthesis of conformationally constrained lysine, ornithine and alanine analogues from pyroglutamic acid
由: Goswami, R, et al.
出版: (1999)

Pyrrolidinones derived from (S)-pyroglutamic acid. Part 1. Conformationally constrained glutamate
由: Bailey, J, et al.
出版: (2000)

Stereocontrolled spirocyclic bislactams derived from pyroglutamic acid
由: Hill, T, et al.
出版: (2006)

Spirocyclic systems derived from pyroglutamic acid.
由: Cowley, A, et al.
出版: (2011)

Functionalised pyrrolidinones derived from (S)-pyroglutamic acid
由: Beard, M, et al.
出版: (1996)

Mimics of pramanicin derived from pyroglutamic acid and their antibacterial activity.
由: Tan, S, et al.
出版: (2017)

Functionalised pyrrolidinones derived from (S)-pyroglutamic acid by cycloaddition reactions
由: Bailey, J, et al.
出版: (1997)

Highly functionalised pyroglutamates by intramolecular aldol reactions: Towards the pyroglutamate skeleton of oxazolomycin
由: Andrews, MD, et al.
出版: (1996)

Synthesis of mimics of pramanicin from pyroglutamic acid and their antibacterial activity.
由: Tan, S, et al.
出版: (2015)

Comparative genomic analysis of azasugar biosynthesis
由: Hailey E. Beal, et al.
出版: (2021-08-01)

Thiouronium Salt Derivatives Based on Vicinal Diamines as Potential Neuroprotectors
由: N. A. Lozinskaya, et al.
出版: (2023-06-01)

(L)-PYROGLUTAMIC ACID AS A CHIRAL STARTING MATERIAL FOR ASYMMETRIC-SYNTHESIS
由: Baldwin, J, et al.
出版: (1991)

Azasugar Glycosidase Inhibitors: Useful Tools for Glycobiologists
由: Sylviane Picasso
出版: (1996-12-01)

Equilibration in bicyclic pyroglutamates by ring opening-reclosure
由: Moloney, M, et al.
出版: (2008)

AMINO-ACID SYNTHESIS USING (L)-PYROGLUTAMIC ACID AS A CHIRAL STARTING MATERIAL
由: Baldwin, J, et al.
出版: (1989)

Intramolecular aldol ring closures of cysteine derivatives leading to densely functionalised pyroglutamates
由: Almahli, H, et al.
出版: (2019)

Natural products-based: Synthesis and antifungal activity evaluation of novel L-pyroglutamic acid analogues
由: Likun Ai, et al.
出版: (2022-12-01)

Synthetic access to 3-substituted pyroglutamic acids from tetramate derivatives of serine, threonine, allo-threonine, and cysteine
由: Bagum, H, et al.
出版: (2019)

Metabolic Acidosis Due To Pyroglutamic Acid
由: Maria João Raposo Linhares Serpa, et al.
出版: (2018-09-01)

Aryldiazirine-modified pyroglutamates: Photoaffinity labels for glutamate
由: Bentz, E, et al.
出版: (2006)

Exploring endoperoxides as a new entry for the synthesis of branched azasugars
由: Svenja Domeyer, et al.
出版: (2017-04-01)

Nitrogen inversion as a diastereomeric relay in azasugar synthesis: the first synthesis of adenophorine.
由: Maughan, M, et al.
出版: (2003)

Diastereoselective intramolecular aldol ring closures of threonine derivatives leading to densely functionalised pyroglutamates related to oxazolomycin
由: Heaviside, E, et al.
出版: (2014)

Diastereoselective reduction of the tricarbonyl moiety in bicyclic tetramates giving pyroglutamates
由: Josa-Culleré, L, et al.
出版: (2018)

Protein engineering of transaminase facilitating enzyme cascade reaction for the biosynthesis of azasugars
由: Yueming Zhu, et al.
出版: (2024-03-01)

Synthetic access to 3,4-disubstituted pyroglutamates from tetramate derivatives from serine, allo-threonine and cysteine
由: Bagum, H, et al.
出版: (2019)

Synthesis of a series of vicinal diamines with potential biological activity
由: Kurteva Vanya, et al.
出版: (2004-12-01)

Three-Step Telescoped Synthesis of Monosubstituted Vicinal Diamines from Aldehydes
由: Lledó Bou-Iserte, et al.
出版: (2019-01-01)

Biomimetic synthesis, antibacterial activity and structure-activity properties of the pyroglutamate core of oxazolomycin
由: Angelov, P, et al.
出版: (2012)

Synthetic Methods for the Preparation of Conformationally Restricted Analogues of Nicotine
由: Biswajit Panda, et al.
出版: (2021-12-01)

The selectivity of galardin and an azasugar-based hydroxamate compound for human matrix metalloproteases and bacterial metalloproteases.
由: Ingebrigt Sylte, et al.
出版: (2018-01-01)

Direct versatile route to conformationally constrained glutamate analogues
由: Dyer, J, et al.
出版: (1998)

Design, Synthesis, and Biological Activity of Conformationally Restricted Analogues of Silibinin
由: Mirei Mizuno, et al.
出版: (2020-08-01)

Synthesis and Biological Evaluation of Lysophosphatidic Acid Analogues Using Conformational Restriction and Bioisosteric Replacement Strategies
由: Mazin A. S. Abdelwahid, et al.
出版: (2023-12-01)

New synthetic seven-membered 1-azasugars displaying potent inhibition towards glycosidases and glucosylceramide transferase.
由: Li, H, et al.
出版: (2008)