Maximum precision closed-form solution for localizing diffraction-limited spots in noisy images.

Super-resolution techniques like PALM and STORM require accurate localization of single fluorophores detected using a CCD. Popular localization algorithms inefficiently assume each photon registered by a pixel can only come from an area in the specimen corresponding to that pixel (not from neighbori...

Full description

Bibliographic Details
Main Authors: Larkin, J, Cook, P
Format: Journal article
Language:English
Published: 2012