Cooperation of Syd-1 with Neurexin synchronizes pre- with postsynaptic assembly.

Cooperation of Syd-1 with Neurexin synchronizes pre- with postsynaptic assembly.

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Synapse formation and maturation requires bidirectional communication across the synaptic cleft. The trans-synaptic Neurexin-Neuroligin complex can bridge this cleft, and severe synapse assembly deficits are found in Drosophila melanogaster neuroligin (Nlg1, dnlg1) and neurexin (Nrx-1, dnrx) mutants...

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Bibliographic Details
Main Authors: Owald, D, Khorramshahi, O, Gupta, V, Banovic, D, Depner, H, Fouquet, W, Wichmann, C, Mertel, S, Eimer, S, Reynolds, E, Holt, M, Aberle, H, Sigrist, S
Format: Journal article
Language:English
Published: 2012

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