Cooperation of Syd-1 with Neurexin synchronizes pre- with postsynaptic assembly.
Synapse formation and maturation requires bidirectional communication across the synaptic cleft. The trans-synaptic Neurexin-Neuroligin complex can bridge this cleft, and severe synapse assembly deficits are found in Drosophila melanogaster neuroligin (Nlg1, dnlg1) and neurexin (Nrx-1, dnrx) mutants...
Main Authors: | Owald, D, Khorramshahi, O, Gupta, V, Banovic, D, Depner, H, Fouquet, W, Wichmann, C, Mertel, S, Eimer, S, Reynolds, E, Holt, M, Aberle, H, Sigrist, S |
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Format: | Journal article |
Language: | English |
Published: |
2012
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