The hypoxia-inducible transcription factor pathway regulates oxygen sensing in the simplest animal, Trichoplax adhaerens.

The hypoxic response in humans is mediated by the hypoxia-inducible transcription factor (HIF), for which prolyl hydroxylases (PHDs) act as oxygen-sensing components. The evolutionary origins of the HIF system have been previously unclear. We demonstrate a functional HIF system in the simplest anima...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Loenarz, C, Coleman, M, Boleininger, A, Schierwater, B, Holland, P, Ratcliffe, P, Schofield, C
स्वरूप: Journal article
भाषा:English
प्रकाशित: 2011