Paternal age effect mutations in germ cell development: pathological correlates in normal testis and testicular tumours
<p>Pathogenic gain-of-function mutations associated with increased paternal age, albeit harmful to embryonic development, are paradoxically enriched in the normal testis. Evidence from previous studies indicates that these so-called paternal age-effect mutations confer a proliferative advantag...
Prif Awdur: | Lim, J |
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Awduron Eraill: | Wilkie, A |
Fformat: | Traethawd Ymchwil |
Iaith: | English |
Cyhoeddwyd: |
2011
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Pynciau: |
Eitemau Tebyg
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