Free energy landscape of lipid interactions with regulatory binding sites on the transmembrane domain of the EGF receptor
Lipid molecules can bind to specific sites on integral membrane proteins, modulating their structure and function. We have undertaken coarse-grained simulations to calculate free energy profiles for glycolipids and phospholipids interacting with modulatory sites on the transmembrane helix dimer of...
| Autores principales: | , , , |
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| Formato: | Journal article |
| Publicado: |
American Chemical Society
2016
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