A guide to super-resolution fluorescence microscopy.
For centuries, cell biology has been based on light microscopy and at the same time been limited by its optical resolution. However, several new technologies have been developed recently that bypass this limit. These new super-resolution technologies are either based on tailored illumination, nonlin...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
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2010
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author | Schermelleh, L Heintzmann, R Leonhardt, H |
author_facet | Schermelleh, L Heintzmann, R Leonhardt, H |
author_sort | Schermelleh, L |
collection | OXFORD |
description | For centuries, cell biology has been based on light microscopy and at the same time been limited by its optical resolution. However, several new technologies have been developed recently that bypass this limit. These new super-resolution technologies are either based on tailored illumination, nonlinear fluorophore responses, or the precise localization of single molecules. Overall, these new approaches have created unprecedented new possibilities to investigate the structure and function of cells. |
first_indexed | 2024-03-07T05:06:17Z |
format | Journal article |
id | oxford-uuid:da0a9675-1021-4974-9e65-0255289a7993 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T05:06:17Z |
publishDate | 2010 |
record_format | dspace |
spelling | oxford-uuid:da0a9675-1021-4974-9e65-0255289a79932022-03-27T09:00:15ZA guide to super-resolution fluorescence microscopy.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:da0a9675-1021-4974-9e65-0255289a7993EnglishSymplectic Elements at Oxford2010Schermelleh, LHeintzmann, RLeonhardt, HFor centuries, cell biology has been based on light microscopy and at the same time been limited by its optical resolution. However, several new technologies have been developed recently that bypass this limit. These new super-resolution technologies are either based on tailored illumination, nonlinear fluorophore responses, or the precise localization of single molecules. Overall, these new approaches have created unprecedented new possibilities to investigate the structure and function of cells. |
spellingShingle | Schermelleh, L Heintzmann, R Leonhardt, H A guide to super-resolution fluorescence microscopy. |
title | A guide to super-resolution fluorescence microscopy. |
title_full | A guide to super-resolution fluorescence microscopy. |
title_fullStr | A guide to super-resolution fluorescence microscopy. |
title_full_unstemmed | A guide to super-resolution fluorescence microscopy. |
title_short | A guide to super-resolution fluorescence microscopy. |
title_sort | guide to super resolution fluorescence microscopy |
work_keys_str_mv | AT schermellehl aguidetosuperresolutionfluorescencemicroscopy AT heintzmannr aguidetosuperresolutionfluorescencemicroscopy AT leonhardth aguidetosuperresolutionfluorescencemicroscopy AT schermellehl guidetosuperresolutionfluorescencemicroscopy AT heintzmannr guidetosuperresolutionfluorescencemicroscopy AT leonhardth guidetosuperresolutionfluorescencemicroscopy |