Lopinavir/ritonavir significantly influences pharmacokinetic exposure of artemether/lumefantrine in HIV-infected Ugandan adults.

BACKGROUND: Treatment of HIV/malaria-coinfected patients with antiretroviral therapy (ART) and artemisinin-based combination therapy has potential for drug interactions. We investigated the pharmacokinetics of artemether, dihydroartemisinin and lumefantrine after administration of a single dose of 8...

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Bibliographic Details
Main Authors: Byakika-Kibwika, P, Lamorde, M, Okaba-Kayom, V, Mayanja-Kizza, H, Katabira, E, Hanpithakpong, W, Pakker, N, Dorlo, T, Tarning, J, Lindegardh, N, de Vries, P, Back, D, Khoo, S, Merry, C
Format: Journal article
Language:English
Published: 2012