Parent-offspring trios: a resource to facilitate the identification of type 2 diabetes genes.
The transmission disequilibrium test with use of trios (an affected proband with both parents) is a robust method for assessing the role of gene variants in disease that avoids the problem of population stratification that may confound conventional case/control studies and allows the detection of pa...
Main Authors: | Frayling, T, Walker, M, McCarthy, M, Evans, J, Allen, L, Lynn, S, Ayres, S, Millauer, B, Turner, C, Turner, R, Sampson, M, Hitman, G, Ellard, S, Hattersley, A |
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格式: | Journal article |
語言: | English |
出版: |
1999
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