Factors affecting the electrocardiographic QT interval in malaria: A systematic review and meta-analysis of individual patient data

Background Electrocardiographic QT interval prolongation is the most widely used risk marker for ventricular arrhythmia potential and thus an important component of drug cardiotoxicity assessments. Several antimalarial medicines are associated with QT interval prolongation. However, interpretation o...

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Main Authors: Chan, XHS, Win, YN, Haeusler, IL, Tan, JY, Loganathan, S, Saralamba, S, Chan, SKS, Ashley, EA, Barnes, KI, Baiden, R, Bassi, PU, Djimde, A, Dorsey, G, Duparc, S, Hanboonkunupakarn, B, ter Kuile, FO, Lacerda, MVG, Nasa, A, Nosten, FH, Onyeji, CO, Pukrittayakamee, S, Siqueira, AM, Tarning, J, Taylor, WRJ, Valentini, G, van Vugt, M, Wesche, D, Day, NPJ, Huang, CL-H, Brugada, J, Price, RN, White, NJ
Format: Journal article
Language:English
Published: Public Library of Science (PLoS) 2020