Monoclonal antibodies for the depletion of specific subpopulations of lymphocytes.

A number of rat monoclonal antibodies of the IgG2b subclass have been used to deplete mice of T lymphocyte subsets. It has been possible to produce long-term depletion where antibodies are administered to mice thymectomized in their adult life, or short-term depletion in euthymic animals. It is ther...

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Bibliographic Details
Main Authors: Waldmann, H, Cobbold, S, Qin, S, Benjamin, R, Nash, T, Welsh, J, Tarnesby, G
Format: Journal article
Language:English
Published: 1987

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