The beta2-adrenergic agonist salbutamol is a potent suppressor of established collagen-induced arthritis: mechanisms of action.

The therapeutic potential of salbutamol, a beta2-adrenergic agonist, was explored in collagen-induced arthritis. This study was based on a report that salbutamol, by elevating intracellular cAMP, inhibits IL-12 production by macrophages and dendritic cells, thus preventing Th1 development. Ten-week-...

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Bibliographic Details
Main Authors: Malfait, A, Malik, A, Marinova-Mutafchieva, L, Butler, D, Maini, R, Feldmann, M
Format: Journal article
Language:English
Published: 1999