Visualization and measurement of DNA methyltransferase activity in living cells.

Visualization and measurement of DNA methyltransferase activity in living cells.

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In this unit, a live-cell assay to measure DNA (cytosine-5) methyltransferase (MTase) activity at the single-cell level is described. This method takes advantage of the irreversible binding of enzymatically active MTases to genomic DNA substituted with the mechanism-based inhibitor 5-aza-2'-deo...

书目详细资料
Main Authors:	Schermelleh, L, Spada, F, Leonhardt, H
格式:	Journal article
语言:	English
出版:	2008

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