Structure-activity relationship studies of novel benzophenones leading to the discovery of a potent, next generation HIV nonnucleoside reverse transcriptase inhibitor.

Despite the progress of the past two decades, there is still considerable need for safe, efficacious drugs that target human immunodeficiency virus (HIV). This is particularly true for the growing number of patients infected with virus resistant to currently approved HIV drugs. Our high throughput s...

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Dades bibliogràfiques
Autors principals: Romines, K, Freeman, G, Schaller, LT, Cowan, JR, Gonzales, S, Tidwell, J, Andrews, C, Stammers, D, Hazen, R, Ferris, R, Short, SA, Chan, J, Boone, L
Format: Journal article
Idioma:English
Publicat: 2006