PARP1 resolves DNA replication defects in PCNA-associated DNA repair disorder

PARP1 resolves DNA replication defects in PCNA-associated DNA repair disorder

<p>Proliferating cell nuclear antigen (PCNA) is an essential cofactor for DNA replication and repair. The toroidal structure of a PCNA trimer makes it a sliding clamp protein, which utilizes its interdomain connecting loop (IDCL) interacting with PIP-box containing proteins to recruit these cl...

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Chi tiết về thư mục
Tác giả chính:	Wang, L
Định dạng:	Luận văn
Ngôn ngữ:	English
Được phát hành:	2019
Những chủ đề:	Cell biology DNA repair DNA replication

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