PARP1 resolves DNA replication defects in PCNA-associated DNA repair disorder
<p>Proliferating cell nuclear antigen (PCNA) is an essential cofactor for DNA replication and repair. The toroidal structure of a PCNA trimer makes it a sliding clamp protein, which utilizes its interdomain connecting loop (IDCL) interacting with PIP-box containing proteins to recruit these cl...
| প্রধান লেখক: | |
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| বিন্যাস: | গবেষণাপত্র |
| ভাষা: | English |
| প্রকাশিত: |
2019
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| বিষয়গুলি: |