PARP1 resolves DNA replication defects in PCNA-associated DNA repair disorder
<p>Proliferating cell nuclear antigen (PCNA) is an essential cofactor for DNA replication and repair. The toroidal structure of a PCNA trimer makes it a sliding clamp protein, which utilizes its interdomain connecting loop (IDCL) interacting with PIP-box containing proteins to recruit these cl...
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| Định dạng: | Luận văn |
| Ngôn ngữ: | English |
| Được phát hành: |
2019
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| Những chủ đề: |