The depletion attraction: an underappreciated force driving cellular organization
Cellular structures are shaped by hydrogen and ionic bonds, plus van der Waals and hydrophobic forces. In cells crowded with macromolecules, a little-known and distinct force - the "depletion attraction" - also acts. We review evidence that this force assists in the assembly of a wide rang...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
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Rockefeller University Press
2006
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_version_ | 1797098306134867968 |
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author | Marenduzzo, D Finan, K Cook, P |
author_facet | Marenduzzo, D Finan, K Cook, P |
author_sort | Marenduzzo, D |
collection | OXFORD |
description | Cellular structures are shaped by hydrogen and ionic bonds, plus van der Waals and hydrophobic forces. In cells crowded with macromolecules, a little-known and distinct force - the "depletion attraction" - also acts. We review evidence that this force assists in the assembly of a wide range of cellular structures, ranging from the cytoskeleton to chromatin loops and whole chromosomes. |
first_indexed | 2024-03-07T05:07:36Z |
format | Journal article |
id | oxford-uuid:da74b6f2-93a5-42b8-815f-ff5ab8dcb186 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T05:07:36Z |
publishDate | 2006 |
publisher | Rockefeller University Press |
record_format | dspace |
spelling | oxford-uuid:da74b6f2-93a5-42b8-815f-ff5ab8dcb1862022-03-27T09:03:26ZThe depletion attraction: an underappreciated force driving cellular organizationJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:da74b6f2-93a5-42b8-815f-ff5ab8dcb186PhysicsPathologyEnglishOxford University Research Archive - ValetRockefeller University Press2006Marenduzzo, DFinan, KCook, PCellular structures are shaped by hydrogen and ionic bonds, plus van der Waals and hydrophobic forces. In cells crowded with macromolecules, a little-known and distinct force - the "depletion attraction" - also acts. We review evidence that this force assists in the assembly of a wide range of cellular structures, ranging from the cytoskeleton to chromatin loops and whole chromosomes. |
spellingShingle | Physics Pathology Marenduzzo, D Finan, K Cook, P The depletion attraction: an underappreciated force driving cellular organization |
title | The depletion attraction: an underappreciated force driving cellular organization |
title_full | The depletion attraction: an underappreciated force driving cellular organization |
title_fullStr | The depletion attraction: an underappreciated force driving cellular organization |
title_full_unstemmed | The depletion attraction: an underappreciated force driving cellular organization |
title_short | The depletion attraction: an underappreciated force driving cellular organization |
title_sort | depletion attraction an underappreciated force driving cellular organization |
topic | Physics Pathology |
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