IL-7-dependent maintenance of ILC3s is required for normal entry of lymphocytes into lymph nodes

IL-7 is essential for the development and homeostasis of T and B lymphocytes and is critical for neonatal lymph node organogenesis because Il7-/- mice lack normal lymph nodes. Whether IL-7 is a continued requirement for normal lymph node structure and function is unknown. To address this, we ablated...

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Hlavní autoři: Yang, J, Cornelissen, F, Papazian, N, Reijmers, R, Llorian, M, Cupedo, T, Coles, M, Seddon, B
Médium: Journal article
Jazyk:English
Vydáno: Rockefeller University Press 2018