Ultrasonic enhancement of photoacoustic emissions by nanoparticle-targeted cavitation
A technique to enhance the photoacoustic emissions from laser-heated nanoparticles is presented. Gold nano particle-doped phantoms are subjected to pulsed optical and ultrasound fields, resulting in bubble formation and collapse and producing strong acoustic emissions. The applied ultrasound field a...
| Main Authors: | , , , |
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| Formato: | Journal article |
| Idioma: | English |
| Publicado em: |
Optical Society of America
2010
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| _version_ | 1826299836077441024 |
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| author | McLaughlan, JR Roy, RA Ju, H Murray, TW |
| author_facet | McLaughlan, JR Roy, RA Ju, H Murray, TW |
| author_sort | McLaughlan, JR |
| collection | OXFORD |
| description | A technique to enhance the photoacoustic emissions from laser-heated nanoparticles is presented. Gold nano particle-doped phantoms are subjected to pulsed optical and ultrasound fields, resulting in bubble formation and collapse and producing strong acoustic emissions. The applied ultrasound field allows for cavitation at lower laser fluences than using light alone. The acoustic emission associated with bubble collapse well exceeds the direct photoacoustic response and is used to image a nanoparticle-doped region in a tissue phantom. The strong acoustic emission and low-threshold fluence associated with ultrasound-assisted cavitation make the technique well suited for nanoparticle-targeted biological imaging and tissue therapy. |
| first_indexed | 2024-03-07T05:08:00Z |
| format | Journal article |
| id | oxford-uuid:da99dd84-6907-4f03-be48-8ab54cf74531 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:08:00Z |
| publishDate | 2010 |
| publisher | Optical Society of America |
| record_format | dspace |
| spelling | oxford-uuid:da99dd84-6907-4f03-be48-8ab54cf745312022-03-27T09:04:20ZUltrasonic enhancement of photoacoustic emissions by nanoparticle-targeted cavitationJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:da99dd84-6907-4f03-be48-8ab54cf74531EnglishSymplectic Elements at OxfordOptical Society of America2010McLaughlan, JRRoy, RAJu, HMurray, TWA technique to enhance the photoacoustic emissions from laser-heated nanoparticles is presented. Gold nano particle-doped phantoms are subjected to pulsed optical and ultrasound fields, resulting in bubble formation and collapse and producing strong acoustic emissions. The applied ultrasound field allows for cavitation at lower laser fluences than using light alone. The acoustic emission associated with bubble collapse well exceeds the direct photoacoustic response and is used to image a nanoparticle-doped region in a tissue phantom. The strong acoustic emission and low-threshold fluence associated with ultrasound-assisted cavitation make the technique well suited for nanoparticle-targeted biological imaging and tissue therapy. |
| spellingShingle | McLaughlan, JR Roy, RA Ju, H Murray, TW Ultrasonic enhancement of photoacoustic emissions by nanoparticle-targeted cavitation |
| title | Ultrasonic enhancement of photoacoustic emissions by nanoparticle-targeted cavitation |
| title_full | Ultrasonic enhancement of photoacoustic emissions by nanoparticle-targeted cavitation |
| title_fullStr | Ultrasonic enhancement of photoacoustic emissions by nanoparticle-targeted cavitation |
| title_full_unstemmed | Ultrasonic enhancement of photoacoustic emissions by nanoparticle-targeted cavitation |
| title_short | Ultrasonic enhancement of photoacoustic emissions by nanoparticle-targeted cavitation |
| title_sort | ultrasonic enhancement of photoacoustic emissions by nanoparticle targeted cavitation |
| work_keys_str_mv | AT mclaughlanjr ultrasonicenhancementofphotoacousticemissionsbynanoparticletargetedcavitation AT royra ultrasonicenhancementofphotoacousticemissionsbynanoparticletargetedcavitation AT juh ultrasonicenhancementofphotoacousticemissionsbynanoparticletargetedcavitation AT murraytw ultrasonicenhancementofphotoacousticemissionsbynanoparticletargetedcavitation |